Fan Yi
Peking University
21 Papers
126 Citations
Fan Yi is an academic researcher from Peking University. The author has contributed to research in topics: Small interfering RNA & RNA. The author has an hindex of 13, co-authored 21 publications. Previous affiliations of Fan Yi include Zhejiang Sci-Tech University.
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Papers
Circulating microRNA-122 as a potential biomarker for liver injury.
Xianfeng Ding,Jianv Ding,Jing Ning,Fan Yi,Jiankui Chen,Deyao Zhao,Jiaping Zheng,Zicai Liang,Zhiyuan Hu,Quan Du +9 more
TL;DR: Serum miR-122 levels were evaluated in acute human hepatotoxicity due to paraquat exposure and another small RNA, U6 small nuclear RNA, was downregulated in hepatocarcinoma patients, suggesting its prognostic significance in this disease.
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Profiling of mismatch discrimination in RNAi enabled rational design of allele-specific siRNAs.
Huang Huang,Ren-Ping Qiao,Deyao Zhao,Tong Zhang,Youxian Li,Fan Yi,Fangfang Lai,Junmei Hong,Xianfeng Ding,Yang Zhenjun,Lihe Zhang,Quan Du,Zicai Liang +12 more
TL;DR: Findings could dramatically simplify the design of allele-specific siRNAs and might also provide guide to increase the specificity of therapeutic si RNAs.
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MicroRNA Profiling in Chinese Patients with Primary Sjögren Syndrome Reveals Elevated miRNA-181a in Peripheral Blood Mononuclear Cells
Linyi Peng,Weizhi Ma,Fan Yi,Yunjiao Yang,Wei Lin,Hua Chen,Xuan Zhang,Lihe Zhang,Fengchun Zhang,Quan Du +9 more
TL;DR: This study led to the speculation that elevated miR-181a levels in the PBMC of these patients compromise the maturation of B cells, enabling them to recognize and attack autoantigens and resulting in disease phenotypes.
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Caged circular siRNAs for photomodulation of gene expression in cells and mice
Lei Zhang,Duanwei Liang,Yuan Wang,Dong Li,Jinhao Zhang,Li Wu,Mengke Feng,Fan Yi,Luzheng Xu,Liandi Lei,Quan Du,Xinjing Tang +11 more
TL;DR: Caged siRNAs with a circular structure were successfully used for photoregulation of target genes in both cells and mice.
RNA-seq identified a super-long intergenic transcript functioning in adipogenesis.
Fan Yi,Feng Yang,Xiaoqiao Liu,Hongbo Chen,Ji Ting,Jiang Lixiang,Xiaoxia Wang,Zhangping Yang,Lihe Zhang,Xianfeng Ding,Zicai Liang,Quan Du +11 more
TL;DR: A dynamic expressional profiling was performed in the induced differentiation of 3T3-L1 cells, and several large intergenic transcripts were found to be upregulated by more than 19-fold during differentiation, contributing to the characterization of a super-long intergenic transcript functioning in adipogenesis.
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