Fan Guo
Sichuan University
9 Papers
25 Citations
Fan Guo is an academic researcher from Sichuan University. The author has contributed to research in topics: Acute kidney injury & Kidney. The author has an hindex of 6, co-authored 9 publications.
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Papers
Pterostilbene, a bioactive component of blueberries, alleviates renal fibrosis in a severe mouse model of hyperuricemic nephropathy
TL;DR: PTE suppressed the activation of TGF-β1/Smad3, Src and STAT3 signaling pathway to alleviate renal fibrosis of HN mice, highlighting that PTE was a potential antifibrotic strategy for hyperuricemic nephropathy.
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Anti-Inflammatory Pyranochalcone Derivative Attenuates LPS-Induced Acute Kidney Injury via Inhibiting TLR4/NF-κB Pathway
TL;DR: It is demonstrated that a potent pyranochalcone derivative, 5b, exhibited renoprotective effect against LPS-induced AKI, which was associated with anti-inflammatory activity by inhibiting the TLR4/NF-κB pathway.
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Selective Histone Deacetylase 6 Inhibitor 23BB Alleviated Rhabdomyolysis-Induced Acute Kidney Injury by Regulating Endoplasmic Reticulum Stress and Apoptosis
Yuying Feng,Rongshuang Huang,Fan Guo,Yan Liang,Jin Xiang,Song Lei,Min Shi,Lingzhi Li,Jing Liu,Yanhuan Feng,Liang Ma,Ping Fu +11 more
TL;DR: In this article, the effect of 23BB on renal tubular cell apoptosis was investigated in a murine model of glycerol (GL) injection-induced rhabdomyolysis.
Pharmacological Inhibition of Fatty Acid-Binding Protein 4 (FABP4) Protects Against Rhabdomyolysis-Induced Acute Kidney Injury.
Rongshuang Huang,Min Shi,Fan Guo,Yuying Feng,Yanhuan Feng,Jing Liu,Lingzhi Li,Yan Liang,Jin Xiang,Song Lei,Liang Ma,Ping Fu +11 more
TL;DR: In this article, the effect of FABP4 in a murine model of glycerol injection-induced rhabdomyolysis was investigated, and it was shown that renal protection of a selective FabP4 inhibitor was substantiated by the reduction of ER stress and inflammation in tubular epithelial cells of RHBYolysis-induced injured kidneys.
Pharmacological inhibition of fatty acid-binding protein 4 (FABP4) protects against renal ischemia-reperfusion injury
Min Shi,Rongshuang Huang,Fan Guo,Lingzhi Li,Yanhuan Feng,Zhengjie Wei,Li Zhou,Liang Ma,Ping Fu +8 more
TL;DR: Findings indicated that FABP4 contributed to the pathogenesis of I/R-induced AKI and suggested that the inhibition of FABp4 might be a promising therapeutic strategy for AKI treatment.