Evanka Madan
All India Institute of Medical Sciences
16 Papers
1 Citations
Evanka Madan is an academic researcher from All India Institute of Medical Sciences. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 2, co-authored 4 publications. Previous affiliations of Evanka Madan include AIIMS, New Delhi.
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Papers
FAT1 acts as an upstream regulator of oncogenic and inflammatory pathways, via PDCD4, in glioma cells
Bhawana Dikshit,Khushboo Irshad,Evanka Madan,Nupur Aggarwal,Chitra Sarkar,P.S. Chandra,Deepak Gupta,P. Chattopadhyay,Subrata Sinha,Kunzang Chosdol +9 more
TL;DR: This study identifies a novel signaling mechanism mediated by FAT1 in regulating the activity of PDCD4 and thereby the key transcription factor AP-1, which then affects known mediators of neoplasia and inflammation.
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FAT1 is a novel upstream regulator of HIF1α and invasion of high grade glioma
Evanka Madan,Bhawana Dikshit,Srinivas H. Gowda,Chitrangda Srivastava,Chitra Sarkar,Parthaprasad Chattopadhyay,Subrata Sinha,Kunzang Chosdol +7 more
TL;DR: For the first time, results reveal an upstream master regulatory role of FAT1 in the expression and role of Hif1α under hypoxic conditions and that FAT1‐HIF1α axis controls the invasiveness of GBM.
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Host SUMOylation Pathway Negatively Regulates Protective Immune Responses and Promotes Leishmania donovani Survival
Jhalak Singhal,Evanka Madan,Ayushi Chaurasiya,Pallavi Srivastava,N. Singh,Shikha Kaushik,Amandeep Kaur Kahlon,Mukesh Maurya,Manisha Marothia,P. Joshi,Anand Ranganathan,Shailja K. J. Singh +11 more
TL;DR: The hijacking of the host SUMOylation pathway by L. donovani toward the suppression of host immune responses and facilitation of host autophagy to potentially facilitate its survival can provide a starting point for the design and development of novel therapeutic interventions to combat leishmaniasis.
Cuscuta reflexa Possess Potent Inhibitory Activity Against Human Malaria Parasite: An In Vitro and In Vivo Study
Sashi Bhusan Ojha,Raj Kumar Sah,Evanka Madan,Ruby Bansal,Shaktirekha Roy,Shailja K. J. Singh,G. Dhangadamajhi +6 more
TL;DR: The findings of the study confirm the antimalarial potential of C. reflexa and exploration of phyto-molecules in GCMS fingerprints of active fractions is warranted for possible identification of lead anti-malarial phy to-drugs.
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Nuclear Factors Linking Cancer and Inflammation
Kunzang Chosdol,Mohita Bhagat,Bhawana Dikshit,Evanka Madan,Parthaprasad Chattopadhyay,Subrata Sinha +5 more
- 01 Jan 2014
TL;DR: This chapter focuses on transcriptional mediators intrinsic to tumour cells that enhance the inflammatory processes, further promoting inflammation, facilitating tumor progression, proliferation, survival and angiogenesis.
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