Eva Borger
University of St Andrews
9 Papers
Eva Borger is an academic researcher from University of St Andrews. The author has contributed to research in topics: Alzheimer's disease & Synapse. The author has an hindex of 8, co-authored 9 publications.
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Papers
Regulation of exosome release from mammary epithelial and breast cancer cells - a new regulatory pathway.
TL;DR: These data suggest a previously unknown novel feedback regulatory mechanism for controlling exosome release, which may highlight a new therapeutic approach to controlling the deleterious effects of tumour exosomes.
253
Activation of a synapse weakening pathway by human Val66 but not Met66 pro-brain-derived neurotrophic factor (proBDNF)
Sumangali Kailainathan,Thomas M. Piers,Jee Hyun Yi,Seongmin Choi,Mark S. Fahey,Eva Borger,F. Gunn-Moore,Laurie O'Neill,Michael Lever,Daniel J. Whitcomb,Kwangwook Cho,Shelley J Allen +11 more
TL;DR: In this article, a fundamental functional difference between the two main polymorphisms of brain-derived neurotrophic factor (proBDNF), providing an explanation as to why these forms have such different age-related neurological outcomes.
34
Mitochondrial β-amyloid in Alzheimer's disease.
Eva Borger,Laura Aitken,Kirsty E. A. Muirhead,Zoe Eleanor Allen,James A. Ainge,Stuart J. Conway,Frank J. Gunn-Moore +6 more
TL;DR: By using a modified peptide approach it is possible to reverse the expression of these two proteins in living transgenic animals and also to recover mitochondrial and behavioural deficits, indicating that the ABAD-Aβ interaction is potentially an interesting target for therapeutic intervention.
Discrimination of bladder cancer cells from normal urothelial cells with high specificity and sensitivity: Combined application of atomic force microscopy and modulated Raman spectroscopy
Elisabetta Canetta,Andrew Riches,Eva Borger,C. Simon Herrington,Kishan Dholakia,Ashok K. Adya +5 more
TL;DR: AFM studies revealed a decrease in the lateral dimensions and an increase in thickness of cancer cells compared to normal cells, which could have a pivotal impact on the development of AFM-Raman combined methodologies for cancer profiling and screening with translational significance.
The consequences of mitochondrial amyloid β-peptide in Alzheimer's disease
TL;DR: The present review explores the possible mechanisms by which cell death occurs, considering the evidence presented on a molecular, cellular and in vivo level.