Esko Levälahti
University of Helsinki
20 Papers
198 Citations
Esko Levälahti is an academic researcher from University of Helsinki. The author has contributed to research in topics: Population & Twin study. The author has an hindex of 17, co-authored 20 publications. Previous affiliations of Esko Levälahti include National Institutes of Health & University of Alberta.
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Papers
Heritability of low back pain and the role of disc degeneration
TL;DR: A classic twin study with multivariate quantitative genetic models found that disc degeneration is one pathway through which genes influence back pain, and a substantial minority of the genetic influences on pain was due to the same genetic influences affecting disc degenerations.
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Genetic and environmental effects on disc degeneration by phenotype and spinal level: a multivariate twin study.
TL;DR: Disc signal, narrowing, and bulging had a primarily common genetic pathway, suggesting a common genetic etiopathogenesis, and genetic and environmental influences differed substantially for upper versus lower lumbar levels, emphasizing the importance of examining these levels separately in studies of associated genes, other constitutional factors, andEnvironmental influences.
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Associations of 25 structural, degradative, and inflammatory candidate genes with lumbar disc desiccation, bulging, and height narrowing.
Tapio Videman,Tapio Videman,Janna Saarela,Jaakko Kaprio,Annu Näkki,Esko Levälahti,Kevin Gill,Leena Peltonen,Michele C. Battié,Michele C. Battié +9 more
TL;DR: Genetic variants account for interindividual differences in disc matrix synthesis and degradation and support the view that disc degeneration is a polygenetic condition.
155
The effects of anthropometrics, lifting strength, and physical activities in disc degeneration.
TL;DR: Body weight, lifting strength, and axial disc area were more highly associated with disc degeneration than occupational and leisure physical activity histories, although all had modest influences.
102
Heritability of BMD of femoral neck and lumbar spine : A multivariate twin study of finnish men
TL;DR: Of the 80% variation in BMD among male twins that is caused by genetics, part was explained by genetic influences on lifting strength and lean body mass/height.
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