Esko Kemppainen
Helsinki University Central Hospital
110 Papers
968 Citations
Esko Kemppainen is an academic researcher from Helsinki University Central Hospital. The author has contributed to research in topics: Acute pancreatitis & Pancreatitis. The author has an hindex of 37, co-authored 107 publications. Previous affiliations of Esko Kemppainen include University of Helsinki.
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Papers
Specific Immunoassay Reveals Increased Serum Trypsinogen 3 in Acute Pancreatitis
Jani Oiva,Outi Itkonen,Riitta Koistinen,Kristina Hotakainen,Wang-Ming Zhang,Esko Kemppainen,Pauli Puolakkainen,Leena Kylänpää,Ulf-Håkan Stenman,Hannu Koistinen +9 more
TL;DR: For the first time a specific immunoassay for trypsinogen 3 is established using monoclonal antibodies and it is found that patients with AP were found to have increased serum concentrations of trypsInogen 3.
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Application of Proteomic Technology in Identifying Pancreatic Secretory Trypsin Inhibitor Variants in Urine of Patients with Pancreatitis
TL;DR: P Pancreatitis-related PSTI variants occurring at nanomolar concentrations in urine can be detected and quantified by immunoaffinity purification and mass spectrometry, and casts new light on the possible role of PSTI as a cause of hereditary pancreatitis.
Serum Serine Peptidase Inhibitor Kazal-Type 1, Trypsinogens 1 to 3, and Complex of Trypsin 2 and α1-Antitrypsin in the Diagnosis of Severe Acute Pancreatitis
Mia Rainio,Outi Lindström,Anne K. Penttilä,Outi Itkonen,Esko Kemppainen,Ulf-Håkan Stenman,Leena Kylänpää +6 more
TL;DR: In this article, the authors explored prediction of severe acute pancreatitis and development of organ dysfunction (OD) using serine peptidase inhibitor Kazal type 1 (SPINK1).
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Early inflammatory response in acute pancreatitis is little affected by body mass index.
TL;DR: In patients with mild AP, BMI correlated positively with CRP levels and inversely with monocyte HLA-DR expression, which might reflect an amplified inflammatory response in these patients.
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