Erin E. Kershaw
University of Pittsburgh
76 Papers
71 Citations
Erin E. Kershaw is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Adipose tissue & Adipose triglyceride lipase. The author has an hindex of 29, co-authored 64 publications. Previous affiliations of Erin E. Kershaw include Beth Israel Deaconess Medical Center.
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Papers
Adipose Tissue as an Endocrine Organ
Erin E. Kershaw,Jeffrey S. Flier +1 more
TL;DR: An overview of the endocrine functions of adipose tissue can be found in this paper, where the authors highlight the adverse metabolic consequences of both adipose excess and deficiency, and propose a more rational therapy for these increasingly prevalent disorders.
ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1
Guenter Haemmerle,Tarek Moustafa,Gerald Woelkart,Sabrina Büttner,Albrecht Schmidt,Tineke van de Weijer,Matthijs K. C. Hesselink,Doris Jaeger,Petra C. Kienesberger,Kathrin A. Zierler,Renate Schreiber,Thomas O. Eichmann,Dagmar Kolb,Petra Kotzbeck,Martina Schweiger,Manju Kumari,Sandra Eder,Gabriele Schoiswohl,Nuttaporn Wongsiriroj,Nina M. Pollak,Franz P.W. Radner,Karina Preiss-Landl,Thomas Kolbe,Thomas Rülicke,Burkert Pieske,Michael Trauner,Achim Lass,Robert Zimmermann,Gerald Hoefler,Saverio Cinti,Erin E. Kershaw,Patrick Schrauwen,Frank Madeo,Bernd Mayer,Rudolf Zechner +34 more
TL;DR: Reconstituting normal PPAR target gene expression by pharmacological treatment of Atgl-deficient mice with PPAR-α agonists completely reverses the mitochondrial defects, restores normal heart function and prevents premature death.
Transcriptional control of adipose lipid handling by IRF4.
Jun Eguchi,Xun Wang,Songtao Yu,Erin E. Kershaw,Patricia C. Chiu,Joanne R. Dushay,Jennifer L. Estall,Ulf Klein,Eleftheria Maratos-Flier,Evan D. Rosen +9 more
TL;DR: It is shown that interferon regulatory factor 4 (IRF4) is a critical determinant of the transcriptional response to nutrient availability in adipocytes and the disposition of calories in adipose tissue, with consequences for systemic metabolic homeostasis.
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Adipose Triglyceride Lipase Function, Regulation by Insulin, and Comparison With Adiponutrin
Erin E. Kershaw,Jonathan K. Hamm,Linda A.W. Verhagen,Odile D. Peroni,Masa Katic,Jeffrey S. Flier +5 more
TL;DR: It is suggested that murine ATGL but not adip Coconutrin contributes to net adipocyte lipolysis and that ATGL and adiponutrin are oppositely regulated by insulin both in vitro and in vivo.
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Molecular Transducers of Physical Activity Consortium (MoTrPAC): Mapping the Dynamic Responses to Exercise.
James A. Sanford,Christopher D. Nogiec,Malene E. Lindholm,Joshua N. Adkins,David Amar,Surendra Dasari,Jonelle K. Drugan,Facundo M. Fernández,Shlomit Radom-Aizik,Simon Schenk,Michael Snyder,Russell P. Tracy,Patrick M. Vanderboom,Scott Trappe,Martin J. Walsh,Charles R. Evans,Yafeng Li,Lyl Tomlinson,D. Lee Alekel,Iddil Bekirov,Amanda T. Boyce,Josephine Boyington,Jerome L. Fleg,Lyndon Joseph,Maren R. Laughlin,Padma Maruvada,Stephanie A. Morris,Joan McGowan,Concepcion R. Nierras,Vinay Pai,Charlotte A. Peterson,Ed Ramos,Mary Roary,John P. Williams,Ashley Xia,Elaine Cornell,Jessica Rooney,Michael Miller,Walter T. Ambrosius,Scott Rushing,Cynthia L. Stowe,W. Jack Rejeski,Barbara J. Nicklas,Marco Pahor,Ching-ju Lu,Todd A. Trappe,Toby Chambers,Ulrika Raue,Bridget Lester,Bryan C. Bergman,David H. Bessesen,Catherine M. Jankowski,Wendy M. Kohrt,Edward L. Melanson,Kerrie L. Moreau,Irene E. Schauer,Robert S. Schwartz,William E. Kraus,Cris A. Slentz,Kim M. Huffman,Johanna L. Johnson,Leslie H. Willis,L S. Kelly,Joseph A. Houmard,Gabriel S. Dubis,Nick Broskey,Bret H. Goodpaster,Lauren M. Sparks,Paul M. Coen,Dan M. Cooper,Fadia Haddad,Tuomo Rankinen,Eric Ravussin,Neil M. Johannsen,Melissa Harris,John M. Jakicic,Anne B. Newman,Daniel Forman,Erin E. Kershaw,Renee J. Rogers,Bradley C. Nindl,Lindsay C. Page,Maja Stefanovic-Racic,Susan Barr,Blake B. Rasmussen,Tatiana Moro,Doug Paddon-Jones,Elena Volpi,Heidi Spratt,Nicolas Musi,Sara E. Espinoza,Darpan I. Patel,Monica C. Serra,Jonathan Gelfond,Aisling Burns,Marcas M. Bamman,Thomas W. Buford,Gary Cutter,Sue C. Bodine,Karyn A. Esser,Rodger P. Farrar,Laurie J. Goodyear,Michael F. Hirshman,Brent G. Albertson,Wei-Jun Qian,Paul D. Piehowski,Marina A. Gritsenko,Matthew E. Monore,Vladislav A. Petyuk,Jason E. McDermott,Joshua N. Hansen,Chelsea Hutchison,Samuel G. Moore,David A. Gaul,Clary B. Clish,Julian Avila-Pacheco,Courtney Dennis,Manolis Kellis,Steve Carr,Pierre M. Jean-Beltran,Hasmik Keshishian,D. R. Mani,Karl R. Clauser,Karsten Krug,Charlie Mundorff,Cadence Pearce,Anna A. Ivanova,Eric A. Ortlund,Kristal M. Maner-Smith,Karan Uppal,Tiantian Zhang,Stuart C. Sealfon,Elena Zaslavsky,Venugopalan D. Nair,SiDe Li,Nimisha Jain,Yongchao Ge,Yifei Sun,German Nudelman,Frederique Ruf-Zamojski,Gregory R. Smith,Nhanna Pincas,Aliza B. Rubenstein,Mary Anne S. Amper,Nitish Seenarine,Tuuli Lappalainen,Ian R. Lanza,K. Sreekumaran Nair,Katherine Klaus,Stephen B. Montgomery,Kevin S. Smith,Bingqing Zhao,Chia-Jiu Hung,Navid Zebarjadi,Brunilda Balliu,Laure Fresard,Charles F. Burant,Jun Li,Maureen Kachman,Tanu Soni,Alexander B. Raskind,Robert E. Gerszten,Jeremy M. Robbins,Olga Ilkayeva,Michael J. Muehlbauer,Christopher B. Newgard,Euan A. Ashley,Matthew T. Wheeler,David Jimenez-Morales,Archana Raja,Karen P. Dalton,Jimmy Zhen,Young Suk Kim,Jeffrey W. Christle,Shruti Marwaha,Elizabeth T Chin,Steven G. Hershman,Trevor Hastie,Robert Tibshirani,Manuel A. Rivas +179 more
TL;DR: The Molecular Transducers of Physical Activity Consortium (MoTrPAC) will provide a public database that is expected to enhance the understanding of the health benefits of exercise and to provide insight into how physical activity mitigates disease.
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