Erik Faessler
University of Jena
25 Papers
92 Citations
Erik Faessler is an academic researcher from University of Jena. The author has contributed to research in topics: Computer science & Biology. The author has an hindex of 9, co-authored 21 publications.
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Papers
IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression
Ahmed Sadik,Luis F. Somarribas Patterson,Selcen Öztürk,Soumya R. Mohapatra,Verena Panitz,Philipp F Secker,Pauline Pfänder,Stefanie Loth,Heba Salem,Mirja Tamara Prentzell,Bianca Berdel,Murat Iskar,Erik Faessler,Friederike Reuter,Isabelle Kirst,Verena Kalter,Kathrin I. Foerster,Evelyn Jäger,Carina Ramallo Guevara,Mansour Sobeh,Thomas Hielscher,Gernot Poschet,Annekathrin Reinhardt,Jessica C. Hassel,Marc Zapatka,Udo Hahn,Andreas von Deimling,Carsten Hopf,Rita Schlichting,Beate I. Escher,Jürgen Burhenne,Walter E. Haefeli,Naveed Ishaque,Alexander Böhme,Sascha Schäuble,Kathrin Thedieck,Saskia Trump,Martina Seiffert,Christiane A. Opitz +38 more
TL;DR: A pan-tissue AHR signature revealed that across 32 tumor entities, interleukin-4-induced-1 (IL4I1) associates more frequently with AHR activity than IDO1 or TDO2, hitherto recognized as the main Trp-catabolic enzymes.
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Event Extraction from Trimmed Dependency Graphs
Ekaterina Buyko,Erik Faessler,Joachim Wermter,Udo Hahn +3 more
- 05 Jun 2009
TL;DR: The approach to event extraction which the JulieLab Team from FSU Jena (Germany) pursued to solve Task 1 in the "BioNLP'09 Shared Task on Event Extraction" is described, incorporating manually curated dictionaries and machine learning methodologies to sort out associated event triggers and arguments on trimmed dependency graph structures.
The PI3K and MAPK/p38 pathways control stress granule assembly in a hierarchical manner
Alexander Martin Heberle,Patricia Razquin Navas,Patricia Razquin Navas,Miriam Langelaar-Makkinje,Katharina Kasack,Katharina Kasack,Ahmed Sadik,Ahmed Sadik,Erik Faessler,Udo Hahn,Philip Marx-Stoelting,Christiane A. Opitz,Christine Sers,Christine Sers,Ines Heiland,Sascha Schäuble,Sascha Schäuble,Kathrin Thedieck,Kathrin Thedieck,Kathrin Thedieck +19 more
- 28 Mar 2019
TL;DR: A new pro-survival function is assigned to the key oncogenic kinases PI3K and p38, as they hierarchically promote stress granule formation as well as the metabolic master regulator mammalian target of rapamycin complex 1.
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Phosphoproteomics identifies dual-site phosphorylation in an extended basophilic motif regulating FILIP1-mediated degradation of filamin-C.
Lena Reimann,Anja N. Schwäble,Anna L. Fricke,Wignand W. D. Mühlhäuser,Yvonne Leber,Keerthika Lohanadan,Martin Puchinger,Sascha Schäuble,Sascha Schäuble,Erik Faessler,Heike Wiese,Heike Wiese,Christa Reichenbach,Bettina Knapp,Christian D. Peikert,Friedel Drepper,Udo Hahn,Clemens Kreutz,Peter F.M. van der Ven,Gerald Radziwill,Kristina Djinović-Carugo,Dieter O. Fürst,Bettina Warscheid +22 more
- 22 May 2020
TL;DR: In this article, the authors studied PI3K/Akt signaling in contracting skeletal muscle cells by quantitative phosphoproteomics and identified the extended basophilic phosphosite motif RxRxxp[S/T]xxp [S/S] for filamin-C (FLNc), which is doubly phosphorylated.
Syntactic simplification and semantic enrichment—trimming dependency graphs for event extraction
Ekaterina Buyko,Erik Faessler,Joachim Wermter,Udo Hahn +3 more
- 01 Nov 2011
TL;DR: The JReX system developed by the JulieLab Team from Friedrich‐Schiller‐Universität Jena (Germany) scored on 2nd rank among 24 competing teams for Task 1 in the “BioNLP’09 Shared Task on Event Extraction” with 45.8% recall, 47.5% precision and 46.7% F1‐score on all 3,182 events.
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