Eric Sheldon
18 Papers
95 Citations
Eric Sheldon is an academic researcher. The author has contributed to research in topics: Immunogenicity & Reactogenicity. The author has an hindex of 14, co-authored 18 publications.
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Papers
Immunogenicity, reactogenicity and safety of an inactivated quadrivalent influenza vaccine candidate versus inactivated trivalent influenza vaccine: a phase III, randomized trial in adults aged ≥18 years
Dorothee Kieninger,Eric Sheldon,Wen-Yuan Lin,Chong-Jen Yu,José M. Bayas,Julian J. Gabor,Meral Esen,Jose Luis Fernandez Roure,Silvia Narejos Perez,C. Sanchez,Yang Feng,Carine Claeys,Mathieu Peeters,Bruce L. Innis,Varsha K. Jain +14 more
TL;DR: QIV provided superior immunogenicity for the additional B strain compared with TIV, without interfering with antibody responses to the three shared antigens, suggesting that the candidate QIV is a viable alternative to TIV for use in adults, and could potentially improve protection against influenza B.
Safety and Cross-Reactive Immunogenicity of Candidate AS03-Adjuvanted Prepandemic H5N1 Influenza Vaccines: A Randomized Controlled Phase 1/2 Trial in Adults
Joanne M. Langley,Louise Frenette,Linda Ferguson,Dennis Riff,Eric Sheldon,George Risi,Casey Johnson,Ping Li,Richard Kenney,Bruce L. Innis,Louis Fries +10 more
TL;DR: The AS03-adjuvanted A/Indonesia/05/2005 (NIBRG-14) vaccines were significantly more immunogenic than nonadjuVanted vaccine in homologous assays and fulfilled European and US licensure criteria for immunogenicity for influenza vaccines.
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Dose-Sparing H5N1 A/Indonesia/05/2005 Pre-pandemic Influenza Vaccine in Adults and Elderly Adults: A Phase III, Placebo-Controlled, Randomized Study
Joanne M. Langley,George Risi,Michael Caldwell,Larry Gilderman,Bruce Berwald,Charles Fogarty,Terry Poling,Dennis Riff,Mira Baron,Louise Frenette,Eric Sheldon,Harry Collins,Marc Shepard,Marc Dionne,Daniel Brune,Linda Ferguson,David W. Vaughn,Ping Li,Louis Fries +18 more
TL;DR: In adults and elderly adults, AS03A-adjuvanted H5N1 candidate vaccine was highly immunogenic for A/Indonesia/05/2005, with cross-reactivity against A/Vietnam/1194/2004.
A phase 1, placebo-controlled, randomized study of the safety, tolerability, and immunogenicity of a Clostridium difficile vaccine administered with or without aluminum hydroxide in healthy adults
Eric Sheldon,Nicholas Kitchin,Yahong Peng,Joseph Eiden,William C. Gruber,J. Erik Johnson,Kathrin U. Jansen,Michael W. Pride,Louise Pedneault +8 more
TL;DR: The data suggest that both the antitoxin A- and B-specific neutralizing responses were trending higher in the toxoids-only groups compared to the toxoid+Al(OH)3 groups, and the magnitude of the immune response was similar in the 2 age cohorts.
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Randomized, double-blind, placebo-controlled, safety and immunogenicity study of 4 formulations of Anthrax Vaccine Adsorbed plus CPG 7909 (AV7909) in healthy adult volunteers
Robert J. Hopkins,Nancy F. Daczkowski,Paulina E. Kaptur,Derek Muse,Eric Sheldon,Craig LaForce,Suha Sari,Thomas L. Rudge,Edward Bernton +8 more
TL;DR: F Frequencies of injection site and systemic reactions recorded by subjects in diaries for 7 days after each injection were highest with AV7909 Formulation 1, and further studies of doses and dosing regimens are planned to assess the immunogenicity and reactogenicity of AV79 09.
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