22 Papers
169 Citations
Eric Salm is an academic researcher from University of Illinois at Urbana–Champaign. The author has contributed to research in topics: Field-effect transistor & Reference electrode. The author has an hindex of 12, co-authored 22 publications. Previous affiliations of Eric Salm include Urbana University.
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Papers
Silicon nanowires with high-k hafnium oxide dielectrics for sensitive detection of small nucleic acid oligomers.
Brian Dorvel,Bobby Reddy,Jonghyun Go,Carlos Duarte Guevara,Eric Salm,Muhammad A. Alam,Rashid Bashir +6 more
TL;DR: A process for fabricating stable HfO(2) dielectric-based silicon nanowires for biosensing applications is described and the effect of surface functionalization on device performance is characterized using the miR-10b DNA analogue as the target sequence and different molecular weight poly-l-lysine as the functionalization layer.
On-chip parallel detection of foodborne pathogens using loop-mediated isothermal amplification
TL;DR: This work demonstrates the multiplexed detection of food pathogens through loop-mediated isothermal amplification on a silicon chip and demonstrates themultiplexed screening of virulence genes of Listeria monocytogenes, Escherichia coli, and Salmonella by dehydrating the corresponding primers in oxidized silicon wells.
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Electrical detection of nucleic acid amplification using an on-chip quasi-reference electrode and a PVC REFET.
Eric Salm,Eric Salm,Yu Zhong,Yu Zhong,Bobby Reddy,Bobby Reddy,Carlos Duarte-Guevara,Carlos Duarte-Guevara,Vikhram V. Swaminathan,Vikhram V. Swaminathan,Yi Shao Liu,Rashid Bashir,Rashid Bashir +12 more
TL;DR: A novel method of utilizing a microfabricated solid-state quasi-reference electrode (QRE) paired with a pH-insensitive reference field effect transistor (REFET) for detection of real-time pH changes is demonstrated.
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Enhanced biosensing resolution with foundry fabricated individually addressable dual-gated ISFETs.
Carlos Duarte-Guevara,Fei Lung Lai,Cheng Chun-Wen,Bobby Reddy,Eric Salm,Vikhram V. Swaminathan,Ying Kit Tsui,Hsiao Chin Tuan,Alex Kalnitsky,Yi Shao Liu,Rashid Bashir +10 more
TL;DR: It is shown that when operated in a "dual-gate" mode, the transistor response can exhibit sensitivities to pH changes beyond the Nernst limit, and an improved resolution can be used to enhance small signals and increase the sensor accuracy when monitoring small pH dynamics in biological reactions.
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Ultralocalized thermal reactions in subnanoliter droplets-in-air
Eric Salm,Carlos Duarte Guevara,Piyush Dak,Brian Dorvel,Bobby Reddy,Muhammad Ashraf Alam,Rashid Bashir +6 more
TL;DR: This method positions droplets on an array of individual silicon microwave heaters on chip to precisely control the temperature of droplets-in-air, allowing us to perform biochemical reactions, including DNA melting and detection of single base mismatches.
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