Eric Patridge
Yale University
22 Papers
73 Citations
Eric Patridge is an academic researcher from Yale University. The author has contributed to research in topics: Flavin mononucleotide & Queer. The author has an hindex of 10, co-authored 21 publications. Previous affiliations of Eric Patridge include Pennsylvania State University.
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Papers
An analysis of FDA-approved drugs: natural products and their derivatives.
TL;DR: In recent years, the declining focus on natural products has impacted the pipeline of NMEs from specific classes, and this trend is likely to continue without specific investment in the pursuit of natural products.
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An analysis of FDA-approved drugs for infectious disease: antibacterial agents.
TL;DR: A study to evaluate all US Food and Drug Administration-approved new molecular entities (NMEs) reveals that the number of new agents targeting infectious disease peaked during the 1990s and declined rapidly thereafter.
118
An analysis of original research contributions toward FDA-approved drugs
TL;DR: Although academia and industry have made similar contributions to the discovery of FDA-approved NMEs, there remains a substantial difference in the gap-to-approval; on average, industry Nmes are 12 years closer to market at the time of the first publication.
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Target selection for FDA-approved medicines.
TL;DR: The mechanistic basis of drug efficacy, with emphasis on target selection, and dynamic trends in targeting over time suggest increasing attention toward novel target families, which presumably reflects increased understanding of disease etiology.
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Tryptophan repressor-binding proteins from Escherichia coli and Archaeoglobus fulgidus as new catalysts for 1,4-dihydronicotinamide adenine dinucleotide-dependent amperometric biosensors and biofuel cells.
TL;DR: Investigation of tryptophan (W) repressor-binding proteins from Escherichia coli and Archaeoglobus fulgidus for possible use in 1,4-dihydronicotinamide adenine dinucleotide (NADH) dependent amperometric biosensors and biofuel cells found results obtained were better than those for EcWrbA.
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