Eric Milne
Rowett Research Institute
62 Papers
990 Citations
Eric Milne is an academic researcher from Rowett Research Institute. The author has contributed to research in topics: Leucine & Urea. The author has an hindex of 29, co-authored 62 publications. Previous affiliations of Eric Milne include University of Aberdeen & St George's Hospital.
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Papers
Hepatic detoxification of ammonia in the ovine liver: possible consequences for amino acid catabolism
Gerald Lobley,Alexmary Connell,Michael A. Lomax,David Stanley Brown,Eric Milne,Alexander Graham Calder,David A.H. Farningham +6 more
TL;DR: Protein synthesis rates in the PDV and liver were unaffected by NH3 infusion but both whole-body and splanchnic tissue leucine oxidation were elevated at the higher rate of administration, and the implications of NH3 detoxification to the energy and N metabolism of the ruminant are discussed.
The role of degradation in the acute control of protein balance in adult man: Failure of feeding to stimulate protein synthesis as assessed by L-[1-13C]leucine infusion
S Melville,Margaret A. McNurlan,K.C. McHardy,John Broom,Eric Milne,Alexander Graham Calder,Peter J. Garlick +6 more
TL;DR: Residual tracer was still detectable in both breath and plasma 12 hours after cessation of a 12-hour tracer infusion, supporting the conclusion that significant errors in estimates of protein turnover due to recycling of label arise with prolonged infusions.
117
Whole-body protein turnover from leucine kinetics and the response to nutrition in human immunodeficiency virus infection
Derek C. Macallan,M.A. McNurlan,Eric Milne,Alexander Graham Calder,P.J. Garlick,George E. Griffin +5 more
TL;DR: HIV infection increases whole-body protein turnover but does not quantitatively impair the acute anabolic response to intravenous nutrition, and this response was quantitatively similar in all groups.
115
Measurement of albumin synthesis in humans: a new approach employing stable isotopes
P. E. Ballmer,Margaret A. McNurlan,Eric Milne,Steven D. Heys,Vivien Buchan,Alexander Graham Calder,Peter J. Garlick +6 more
TL;DR: A new method for measuring albumin synthesis in humans with stable isotopes is presented, which can readily be applied in most clinical conditions, even when albumin losses are occurring or when repeated assessment is required.
105
Urea recycling in sheep: effects of intake.
TL;DR: The present model predicted that 95% of the label movements across the GIT could be accommodated by three or fewer entries and returns of urea-N and 99% by recycling for a maximum of six occasions, and offered a relatively simple means of estimating anabolic reuse of Urea by digestive tract micro-organisms.