Eric Merle
5 Papers
6 Citations
Eric Merle is an academic researcher. The author has contributed to research in topics: Perfusion & Medicine. The author has an hindex of 1, co-authored 2 publications.
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Papers
3D deconvolution of human skin immune architecture with Multiplex Annotated Tissue Imaging System
M. Scholaert,Raïssa Houmadi,Jeremy Martin,Nadine Serhan,Marie Tauber,E. Braun,L. Basso,Eric Merle,Pascal Descargues,Manuelle Viguier,Cécile Lesort,Benoît Chaput,Jean Kanitakis,Denis Jullien,Cristina Bulai Livideanu,Laurence Lamant,Emeline Pages,Nicolas Gaudenzio +17 more
TL;DR: In this paper , a flexible analytic pipeline for spatially resolved immune phenotyping of the skin in experimental or clinical samples is introduced, based on phenotype attribution matrices coupled with α-shape algorithms.
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Liver function during extracorporeal whole liver perfusion in a pig model of acute ischemic liver failure.
Isabelle Mechet,Franck Lhuillier,Marie Cécile Blanchet,Michel Pouyet,J. P. Viale,Joëlle Goudable,G. Annat,Jean-Yves Scoazec,Olivier Boillot,Dominique Liotard,Eric Merle,Bertrand Delafosse +11 more
TL;DR: In an acute ischemic liver failure pig model, an extra corporeal whole liver perfusion demonstrated detoxification properties as well as synthesis capacities.
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3-D deconvolution of human skin immune architecture with Multiplex Annotated Tissue Imaging System (MANTIS)
M. Scholaert,Raïssa Houmadi,Jeremy Martin,Nadine Serhan,Marie Tauber,E. Braun,L. Basso,Eric Merle,Pascal Descargues,Manuelle Viguier,Cécile Lesort,Benoît Chaput,Jean Kanitakis,Denis Jullien,Cristina Bulai Livideanu,Laurence Lamant,Emeline Pages,Nicolas Gaudenzio +17 more
TL;DR: Based on phenotype attribution matrices coupled to α-shape algorithms, MANTIS as mentioned in this paper projects a representative digital immune landscape, while enabling automated detection of major inflammatory clusters and concomitant single-cell data quantification of biomarkers.
Uncoupling the systemic circulation and the ex vivo circuit during experimental isolated liver perfusion
Franck Lhuillier,Michel Pouyet,Isabelle Mechet,Dominique Liotard,Eric Merle,Bertrand Delafosse,Joëlle Goudable,Christine Vianey-Saban,J. P. Viale +8 more
TL;DR: In an ischemic-induced liver failure pig model, a circuit allowing low flows going out of and into the systemic circulation, whereas the flow going through the ex vivo liver is maintained at a high value is developed, which represents an extracorporeal circuit that could be used in place of the direct extracordoreal high-flow liver perfusion.
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Multi-modal profiling of biostabilized human skin modules reveals a coordinated ecosystem response to injected mRNA-1273 COVID-19 vaccine
M. Scholaert,Mathias Peries,Emilie Braun,Jeremy Martin,Nadine Serhan,Alexia Loste,Audrey Bruner,L. Basso,Benoît Chaput,Eric Merle,Pascal Descargues,Emeline Pagès,N. Gaudenzio +12 more
TL;DR: VaxSkin, a flexible solution designed for the comprehensive monitoring of the natural human skin ecosystem’s response to vaccines over time, provides a multiscale vision of skin vaccination that could pave the way toward the development of new vaccination development strategies.