Eric McLaughlin
Ohio State University
55 Papers
39 Citations
Eric McLaughlin is an academic researcher from Ohio State University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 5, co-authored 23 publications.
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Papers
Arming an oncolytic herpes simplex virus Type 1 with a single chain fragment variable antibody against PD-1 for experimental glioblastoma therapy.
Carmela Passaro,Quazim A. Alayo,Isabel DeLaura,John McNulty,Korneel Grauwet,Hirotaka Ito,Vivek Bhaskaran,Marco Mineo,Sean E. Lawler,Khalid Shah,Maria C. Speranza,Maria C. Speranza,William F. Goins,Eric McLaughlin,Soledad Fernandez,David A. Reardon,Gordon J. Freeman,E. Antonio Chiocca,Hiroshi Nakashima +18 more
TL;DR: In situ NG34scFvPD-1 treatment improved the survival with a tail of durable survivorship in 2 syngeneic immunocompetent mouse models of GBM with evidence for antitumor memory.
Phase 2 study of ibrutinib in classic and variant hairy cell leukemia.
Kerry A. Rogers,Leslie A. Andritsos,Lai Wei,Eric McLaughlin,Amy S. Ruppert,Mirela Anghelina,James S. Blachly,Timothy G. Call,Dai Chihara,Anees M. Dauki,Ling Guo,S. Percy Ivy,Lacey R. James,Dan Jones,Robert J. Kreitman,Gerard Lozanski,David M. Lucas,Apollinaire Ngankeu,Mitch A. Phelps,Farhad Ravandi,Charles A. Schiffer,William E. Carson,Jeffrey A. Jones,Michael R. Grever +23 more
TL;DR: Ibrutinib as mentioned in this paper, an oral agent targeting Bruton tyrosine kinase in the B-cell receptor signaling pathway, is highly effective in several malignancies.
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Host cell perforation by listeriolysin O (LLO) activates a Ca2+-dependent cPKC/Rac1/Arp2/3 signaling pathway that promotes Listeria monocytogenes internalization independently of membrane resealing
Jonathan G. T. Lam,Jonathan G. T. Lam,Stephen Vadia,Sarika Pathak-Sharma,Eric McLaughlin,Xiaoli Zhang,Joel A. Swanson,Stephanie Seveau,Stephanie Seveau +8 more
TL;DR: This work has identified key transducers activated upon host cell perforation by the pore-forming toxin LLO to promote Listeria entry, distinct from the pathway that reseals the toxin-perforated cell.
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Prevalence and predictors of peripheral neuropathy after breast cancer treatment.
Mandana Kamgar,Mark K. Greenwald,Hadeel Assad,Theresa A. Hastert,Eric McLaughlin,Kerryn W. Reding,Electra D. Paskett,Jennifer W. Bea,Aladdin H. Shadyab,Marian L. Neuhouser,Rami Nassir,Tracy E. Crane,Kalyan Sreeram,Michael S. Simon +13 more
TL;DR: In this article, the prevalence and predictors of peripheral neuropathy among women with breast cancer followed in the Women's Health Initiative's Life and Longevity After Cancer survivorship cohort were assessed using the Functional Assessment of Cancer Therapy-Gynecologic Oncology Group/Neurotoxicity instrument.
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Conization pathologic features as a predictor of intermediate and high risk features on radical hysterectomy specimens in early stage cervical cancer.
Megan L. Hutchcraft,Blair Smith,Eric McLaughlin,Erinn M. Hade,Floor J. Backes,David M. O'Malley,David E. Cohn,Jeffrey M. Fowler,Larry J. Copeland,Ritu Salani +9 more
TL;DR: Evaluating the additive value of pathologic features of a cone biopsy toward identifying patients with high risk tumors for which adjuvant therapy may be indicated found presence of LVSI in the conization was associated with intermediate risk criteria in 60% of cases and high risk criterion in 37% of Cases.
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