Eric Johannsen
University of Wisconsin-Madison
71 Papers
221 Citations
Eric Johannsen is an academic researcher from University of Wisconsin-Madison. The author has contributed to research in topics: Epstein–Barr virus & Lytic cycle. The author has an hindex of 34, co-authored 65 publications. Previous affiliations of Eric Johannsen include Brigham and Women's Hospital & Harvard University.
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Papers
Proteins of purified Epstein-Barr virus
Eric Johannsen,Micah A. Luftig,Michael R. Chase,Steve Weicksel,Ellen Cahir-McFarland,Diego Illanes,David A. Sarracino,Elliott Kieff +7 more
TL;DR: Mature Epstein-Barr virus was purified from the culture medium of infected lymphocytes made functionally conditional for Zta activation of lytic replication by an in-frame fusion with a mutant estrogen receptor.
490
The Epstein-Barr virus nuclear antigen 2 transactivator is directed to response elements by the J kappa recombination signal binding protein.
TL;DR: Purified or recombinant in vitro-translated J kappa binds to the MNYYGTGGGAA EBNA-2 response element sequence and interacts with EBNA, but does not bind to theJ kappa 1 heptamer recombination signal sequence.
385
Pyogenic liver abscesses.
TL;DR: The classic triad of fever, upper right quadrant pain or fullness, and jaundice resulting from advanced pylephlebitis is now seldom seen.
244
Epstein-Barr Virus Oncoprotein Super-enhancers Control B Cell Growth
Hufeng Zhou,Hufeng Zhou,Stefanie C.S. Schmidt,Stefanie C.S. Schmidt,Sizun Jiang,Sizun Jiang,Bradford Willox,Katharina Bernhardt,Katharina Bernhardt,Jun Liang,Jun Liang,Eric Johannsen,Peter V. Kharchenko,Benjamin E. Gewurz,Benjamin E. Gewurz,Elliott Kieff,Elliott Kieff,Bo Zhao,Bo Zhao +18 more
TL;DR: In insight into mechanisms of EBV-induced lymphoproliferation and potential therapeutic interventions, EBV super-enhancer-associated genes included the MYC and BCL2 oncogenes, which enable LCL proliferation and survival are provided.
179
Epstein-Barr virus nuclear antigens 3C and 3A maintain lymphoblastoid cell growth by repressing p16INK4A and p14ARF expression
TL;DR: EBNA3C and EBNA3A joint repression of CDKN2A p16INK4A and p14ARF is essential for LCL growth, indicating that EBV conversion of primary human B lymphocytes into continuously proliferating lymphoblast cell lines (LCLs) and for maintaining LCLgrowth are each essential.
135