Eric Finlay
Leeds Teaching Hospitals NHS Trust
7 Papers
9 Citations
Eric Finlay is an academic researcher from Leeds Teaching Hospitals NHS Trust. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 4, co-authored 4 publications.
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Papers
Factor H autoantibody is associated with atypical hemolytic uremic syndrome in children in the United Kingdom and Ireland
Vicky Brocklebank,Sally Johnson,Thomas P. Sheerin,Stephen D. Marks,Rodney D. Gilbert,Kay Tyerman,Meredith Kinoshita,Atif Awan,Amrit Kaur,Nicholas J. A. Webb,Shivaram Hegde,Eric Finlay,Maggie Fitzpatrick,Patrick R. Walsh,Edwin K.S. Wong,Caroline J. Booth,Larissa Kerecuk,Alan D. Salama,Michael Almond,Carol Inward,Timothy H.J. Goodship,Neil S. Sheerin,Kevin J. Marchbank,David J. Kavanagh +23 more
TL;DR: Current practice is to initiate eculizumab therapy for treatment of factor H autoantibody–mediated atypical hemolytic uremic syndrome rather than plasma exchange with or without immunosuppression, although the strength of the conclusions is limited by the small sample size.
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Long-term outcomes and response to treatment in diacylglycerol kinase epsilon nephropathy.
Vicky Brocklebank,Vicky Brocklebank,Gurinder Kumar,Alexander J. Howie,Jayanthi Chandar,David V. Milford,Janet Craze,Jonathan Evans,Eric Finlay,Michael Freundlich,Daniel P. Gale,Carol Inward,Martin Mraz,Caroline Jones,William Wong,Stephen D. Marks,John O. Connolly,Bronte M. Corner,Kate Smith-Jackson,Kate Smith-Jackson,Patrick R. Walsh,Patrick R. Walsh,Kevin J. Marchbank,Kevin J. Marchbank,Claire L. Harris,Claire L. Harris,Valerie Wilson,Edwin K.S. Wong,Michal Malina,Michal Malina,Sally Johnson,Sally Johnson,Neil S. Sheerin,Neil S. Sheerin,David J. Kavanagh,David J. Kavanagh +35 more
TL;DR: Analysis of pathological features reveals that DGKE mutations give an MPGN-like appearance to different extents, with but more often without changes in arterioles or arteries, suggesting that in individuals who currently receive eculizumab therapy it can be safely withdrawn.
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Focal segmental glomerulosclerosis in a female patient with Donnai-Barrow syndrome.
Ihab Sakr Shaheen,Eric Finlay,Katrina Prescott,Meaghan K. Russell,Mauro Longoni,Shelagh Joss +5 more
TL;DR: The patient was born by normal vaginal delivery at 38 weeks to consanguineous parents and was noted to have bilateral iris colobomata, downslanting palpebral fissures, hypertelorism, a broad nasal root and flattened nasal tip, a wide philtrum and low-set ears.
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Intensive compared with less intensive blood pressure control to prevent adverse cardiac remodelling in children with chronic kidney disease (HOT-KID): a parallel-group, open-label, multicentre, randomised, controlled trial
Manish D. Sinha,Haotian Gu,Abdel Douiri,Janette Cansick,Eric Finlay,Rodney D. Gilbert,Larissa Kerecuk,Andrew Lunn,Heather Maxwell,Henry Morgan,Mohan Shenoy,Rukshana Shroff,P Subramaniam,Jane Tizard,Yincent Tse,Reza Rezavi,John M. Simpson,Philip Chowienczyk +17 more
TL;DR: HOT-KID hypothesised that lower blood pressure would reduce adverse cardiac remodelling in children with chronic kidney disease and results suggest that optimal target blood pressure levels are close to the 50th percentile.
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Daily low-dose prednisolone to prevent relapse of steroid-sensitive nephrotic syndrome in children with an upper respiratory tract infection: PREDNOS2 RCT.
Martin Christian,Nicholas J. A. Webb,Rebecca Woolley,Nafsika Afentou,Samir Mehta,Emma Frew,Elizabeth Brettell,Adam Khan,David V. Milford,Detlef Bockenhauer,Moin A. Saleem,Angela S Hall,Ania Koziell,Heather Maxwell,Shivaram Hegde,Eric Finlay,Rodney D. Gilbert,Caroline Jones,Karl McKeever,Wendy Cook,Natalie Ives +20 more
TL;DR: Giving 6 days of daily low-dose prednisolone at the time of an upper respiratory tract infection does not reduce the risk of relapse of steroid-sensitive nephrotic syndrome in UK children, but there was an economic benefit from costs associated with background therapy and relapse, and the health-related quality-of-life impact of having a relapse.
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