https://genoplivning.dk/wp-content/uploads/2013/07/european-resuscitation-council-guidelines-for-resuscitation-2010-section-4-adult-advanced-life-support.pdf

European Resuscitation Council Guidelines for Resuscitation 2010 Section 4 Adult advanced life support

European Resuscitation Council Guidelines for Resuscitation 2010 Section 4. Adult advanced life support.

https://anestesiar.org/WP/uploads/2011/01/7-neonatos-ERC-2010.pdf

European Resuscitation Council Guidelines for Resuscitation 2010 Section 1. Executive summary.

European Resuscitation Council Guidelines 2021: Adult advanced life support.

In the face of a crisis in organ donation, the transplant community are increasingly utilizing donation after circulatory death (DCD) donors. Over the last 10 years, with the increasing usage of DCD donors, we have seen the introduction in a number of new terms and definitions. We report the results of the 6th International Conference in Organ Donation held in Paris in 2013 and report a consensus agreement of an established expert European Working Group on the definitions and terminology regarding DCD donation, including refinement of the Maastricht definitions. This document forms part of a special series where recommendations are presented for uncontrolled and controlled DCD donation and organ specific guidelines for kidney, pancreas, liver and lung transplantation. An expert panel formed a consensus on definitions and terms aiming to establish consistent usage of terms in DCD donation.

https://onlinelibrary.wiley.com/doi/pdf/10.1111/tri.12776

New Classification of Donation after Circulatory Death Donors Definitions and Terminology

BACKGROUND This prospective observational study aimed to assess the relevance of serial postoperative plasma neutrophil gelatinase-associated lipocalin (NGAL) measurements on prediction of early renal transplant function. METHODS Plasma NGAL (pNGAL) was measured (Triage NGAL Test; Biosite Inc., Inverness Medical) in 41 patients scheduled for kidney transplantation from deceased or living donors, immediately before and after surgery, and at 12 hr, day 1, day 3, and day 7. A delayed graft function (DGF) was defined as the need for dialysis during the first week. The results were expressed as median (Q1, Q3). RESULTS Of the 41 consecutive patients enrolled, all had a high preoperative pNGAL level: 453 ng/mL (382, 595). Fifteen (36.6%) presented a DGF. In patients with DGF, pNGAL was significantly higher at 12 hr (571 [467, 634] vs. 242 [158, 299] ng/mL, P<0.0001) and at day 1 (466 [356, 627] vs. 165 [91, 248] ng/mL, P<0.0001). A pNGAL higher than 400 ng/mL 12 hr after transplantation predicted DGF with a sensitivity of 93.3%, a specificity of 88.5%, and an odds ratio of 63.2 (P=0.0004). This predictive performance was higher than for plasma creatinine. CONCLUSIONS pNGAL level early and accurately predicted DGF after renal transplantation. pNGAL measurements allowed monitoring of the renal function in this striking situation of ischemia-reperfusion aggression. Early identification of patients at risk of DGF, before graft lesions are consolidated, opens the field of a precise monitoring of renal injury and the impact of future protective therapeutics.

Plasma neutrophil gelatinase-associated lipocalin in kidney transplantation and early renal function prediction.

Impaired microcirculation and tubule injuries explain the changes in kidney function during and after surgery. Surgery is a risk factor for acute renal failure, the incidence of which ranges from 0.8% to 40%, depending on the kind of surgery. Mortality due to perioperative acute renal failure ranges from 17% to 60%, depending on the kind of surgery. For almost 10 to 20% of survivors, acute renal failure becomes chronic. Of the various definitions of acute renal failure, the RIFLE classification(risk of renal dysfunction, injury to the kidney, failure of kidney function, loss of kidney function, end-stage kidney disease)is a consensus definition for predicting hospital mortality. Preoperative renal function was based on serum creatinine and creatinine clearance, calculated with either the Cockcroft and Gault or modification of diet in renal disease (MDRD) formula. Predictors of postoperative acute renal failure include: previous renal dysfunction (most predictive), age older than 56 years, peripheral vascular occlusive disease, chronic obstructive pulmonary disease, congestive heart failure, hypertension and diabetes mellitus, body mass index over 32, use of a vasopressor infusion and diuretic administration, emergency or major surgery, and liver disease. Biomarkers for acute kidney injury are useful for diagnosis of early renal dysfunction. The most promising of these isneutrophil gelatinase-associated lipocalin(NGAL). Renal protection consists in maintaining an optimal blood volume and cardiac output. Nephrotoxic agents always must be removed.

Modifications péri-opératoires de la fonction rénale

Fatal intraurethral foreign body

Publication outcome of abstracts presented at an Anesthesiology and Critical Care Medicine meeting: Does being a junior presenter matter?

This Provisional PDF corresponds to the article as it appeared upon acceptance. Copyedited and fully formatted PDF and full text (HTML) versions will be made available soon. Kidney retrieval after sudden out of hospital refractory cardiac arrest: a cohort of uncontrolled non heart beating donors

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