Eric Benoist
University of Toulouse
71 Papers
425 Citations
Eric Benoist is an academic researcher from University of Toulouse. The author has contributed to research in topics: Chemistry & Ligand. The author has an hindex of 15, co-authored 66 publications. Previous affiliations of Eric Benoist include Paul Sabatier University & Centre national de la recherche scientifique.
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Papers
Overview of Radiolabeled Somatostatin Analogs for Cancer Imaging and Therapy.
Romain Eychenne,Christelle Bouvry,Mickael Bourgeois,Pascal Loyer,Eric Benoist,Nicolas Lepareur +5 more
TL;DR: The development of somatostatin analogs are reviewed, from the well-established and authorized ones to the most recently developed radiotracers, which have better pharmacokinetic properties and demonstrate increased efficacy and safety, as well as the search for new clinical indications.
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Rhenium(I) and technetium(I) complexes of a novel pyridyltriazole-based ligand containing an arylpiperazine pharmacophore: Synthesis, crystal structures, computational studies and radiochemistry
Achour Seridi,Achour Seridi,Mariusz Wolff,Alexandre Boulay,Alexandre Boulay,Nathalie Saffon,Yvon Coulais,Claude Picard,Claude Picard,Barbara Machura,Eric Benoist,Eric Benoist +11 more
TL;DR: The preparation of two M(CO)3 complexes from a novel pyridyltriazole-based ligand 2 bearing the bioactive (2-methoxyphenyl)piperazine pharmacophore presented a suitable lipophilic character for its use as a CNS imaging agent.
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Tricarbonyl ReI Complexes from Functionalised Pyridine–Triazole Derivatives: From Mononuclear to Unexpected Dimeric Complexes
Alexandre Boulay,Achour Seridi,Chantal Zedde,Sonia Ladeira,Claude Picard,Laurent Maron,Eric Benoist +6 more
TL;DR: In this article, a series of structurally related complexes in which bipy is replaced by pyridine-triazole ligands (or pyta) bearing a pendant acetyl group on the triazole ring were obtained.
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Efficient and tunable synthesis of new polydentate bifunctional chelating agents using click chemistry
TL;DR: Two novel bifunctional chelating agents, which are bistriazole-based polyaminocarboxylic acids, have been designed and synthesised in high yields and an elegant synthetic approach using the Cu-catalysed azide–alkyne cycloaddition has been developed.
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A click procedure with heterogeneous copper to tether technetium-99m chelating agents and rhenium complexes. Evaluation of the chelating properties and biodistribution of the new radiolabelled glucose conjugates.
Eric Benoist,Yvon Coulais,Mehdi Almant,José Kovensky,Vincent Moreau,David Lesur,Marine Artigau,Claude Picard,Chantal Galaup,Sébastien G. Gouin +9 more
TL;DR: An efficient protocol was developed to tether chelating agents and rhenium complexes onto a glucoside scaffold with a heterogeneous copper catalyst via click chemistry and M(CO)(3)-glucoconjugates displayed excellent in vitro stability, a fast in vivo blood clearance and a low specific organ uptake or long-term retention in spleen and stomach.
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