Enos Kline
University of Washington
17 Papers
76 Citations
Enos Kline is an academic researcher from University of Washington. The author has contributed to research in topics: Loop-mediated isothermal amplification & Biology. The author has an hindex of 8, co-authored 12 publications. Previous affiliations of Enos Kline include University of Colorado Denver.
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Papers
A rapid, instrument-free, sample-to-result nucleic acid amplification test
Lisa Lafleur,Joshua D. Bishop,Erin K. Heiniger,Ryan Gallagher,Maxwell Wheeler,Peter Kauffman,Xiaohong Zhang,Enos Kline,Joshua R. Buser,Sujatha Kumar,Samantha A. Byrnes,Nicolaas M. J. Vermeulen,Noah Scarr,Yevgeniy S. Belousov,Walt Mahoney,Bhushan J. Toley,Paula D. Ladd,Barry R. Lutz,Paul Yager +18 more
TL;DR: The MAD NAAT prototype was used to characterize a set of human nasal swab specimens pre-screened for methicillin-resistant Staphylococcus aureus bacteria, and consistently detected MRSA in these specimens.
162
Patient-derived luminal breast cancer xenografts retain hormone receptor heterogeneity and help define unique estrogen-dependent gene signatures
Peter Kabos,Jessica Finlay-Schultz,Chunling Li,Enos Kline,Christina Finlayson,Joshua Wisell,Christopher A Manuel,Susan M. Edgerton,J. Chuck Harrell,Anthony D. Elias,Carol A. Sartorius +10 more
TL;DR: Patient-derived ER+ luminal breast tumor models for the study of intratumoral hormone and receptor action are described and the importance of primary xenografts for improved understanding of ER+ breast cancer heterogeneity and development of personalized therapies is underscored.
Isothermal strand displacement amplification (iSDA): a rapid and sensitive method of nucleic acid amplification for point-of-care diagnosis.
Bhushan J. Toley,Isabela Covelli,Yevgeniy S. Belousov,Sujatha Ramachandran,Enos Kline,Noah Scarr,Nic Vermeulen,Walt Mahoney,Barry R. Lutz,Paul Yager +9 more
TL;DR: Isothermal strand displacement amplification (iSDA) as discussed by the authors can achieve >10(9)-fold amplification of the target sequence in <20 minutes at 49 °C, which makes it one of the fastest existing isothermal DNA amplification methods.
OLA-Simple: A software-guided HIV-1 drug resistance test for low-resource laboratories.
Nuttada Panpradist,Ingrid A. Beck,Justin D. Vrana,Nikki Higa,Nikki Higa,David McIntyre,Parker S. Ruth,Isaac So,Enos Kline,Ruth Kanthula,Ruth Kanthula,Ruth Kanthula,Annie Wong-On-Wing,Annie Wong-On-Wing,Jonathan Lim,Daisy Ko,Ross S. Milne,Theresa M. Rossouw,Ute Dagmar Feucht,Ute Dagmar Feucht,Michael H. Chung,Gonzague Jourdain,Nicole Ngo-Giang-Huong,Laddawan Laomanit,Jaime Soria,James J. Lai,Eric Klavins,Lisa M. Frenkel,Barry R. Lutz +28 more
TL;DR: The reduced complexity, cost, and training requirements of OLA-Simple could improve access to HIVDR testing in low-resource settings and potentially allow same-day selection of appropriate antiretroviral therapy.
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Alternative Polyadenylation of PRELID1 Regulates Mitochondrial ROS Signaling and Cancer Outcomes.
Austin E. Gillen,Heather M. Brechbuhl,Tomomi M. Yamamoto,Enos Kline,Manoj M. Pillai,Jay R. Hesselberth,Peter Kabos +6 more
TL;DR: Modulation of PRELID1 expression, including its posttranscriptional control, appears to be a common stress response across different cancer types and represents a novel prognostic factor and therapeutic target in cancer.