Emma Thomas
University of Manchester
18 Papers
2 Citations
Emma Thomas is an academic researcher from University of Manchester. The author has contributed to research in topics: Citalopram & Major depressive disorder. The author has an hindex of 15, co-authored 18 publications.
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Papers
State-dependent changes in hippocampal grey matter in depression.
Danilo Arnone,Shane McKie,Rebecca Elliott,Gabriella Juhasz,Gabriella Juhasz,Emma Thomas,Darragh Downey,Steven Williams,John Francis William Deakin,Ian M. Anderson +9 more
TL;DR: An increase in grey matter was observed in the hippocampus following treatment with citalopram in currently depressed patients, and this is a potential biomarker for a depressive episode.
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Increased Amygdala Responses to Sad But Not Fearful Faces in Major Depression: Relation to Mood State and Pharmacological Treatment
Danilo Arnone,Shane McKie,Rebecca Elliott,Emma Thomas,Darragh Downey,Gabriella Juhasz,Steve R. Williams,J.F. William Deakin,Ian M. Anderson +8 more
TL;DR: Aberrant amygdala activation in response to sad facial emotions is specific to the depressed state and is a potential biomarker for a negative affective bias during a depressive episode.
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The CREB1-BDNF-NTRK2 pathway in depression: multiple gene-cognition-environment interactions
Gabriella Juhasz,Jason S. Dunham,Shane McKie,Emma Thomas,Darragh Downey,Diana Chase,Kathryn Lloyd-Williams,Zoltan G. Toth,Hazel Platt,Krisztina Mekli,Krisztina Mekli,Antony Payton,Rebecca Elliott,Steve R. Williams,Ian M. Anderson,J.F. William Deakin +15 more
TL;DR: Genetic variation associated with reduced function in the CREB1-BDNF-NTRK2 pathway has multiple, sometimes opposing, influences on risk mechanisms of depression, but almost all the SNPs studied amplified the effect of childhood adversity.
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State-dependent alteration in face emotion recognition in depression.
Ian M. Anderson,Clare Shippen,Gabriella Juhasz,Diana Chase,Emma Thomas,Darragh Downey,Zoltan G. Toth,Kathryn Lloyd-Williams,Rebecca Elliott,J.F. William Deakin +9 more
TL;DR: Abnormalities in face emotion recognition differ between people with current depression and those in remission, which may relate to the known effects of antidepressants on emotional processing and could contribute to their ability to protect against depressive relapse.
Reversed Frontotemporal Connectivity During Emotional Face Processing in Remitted Depression
Nia Goulden,Shane McKie,Emma Thomas,Darragh Downey,Gabriella Juhasz,Stephen R. Williams,James B. Rowe,J.F. William Deakin,Ian M. Anderson,Rebecca Elliott +9 more
TL;DR: Processing of mood incongruent happy information was associated with a more richly modulated frontotemporal brain network, whereas mood congruent sad information wasassociated with less network modulation, which supports a hypothesis of dysfunction within cortico–limbic connections in individuals vulnerable to depression.
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