Emma Carmelo
University of La Laguna
21 Papers
93 Citations
Emma Carmelo is an academic researcher from University of La Laguna. The author has contributed to research in topics: Leishmania braziliensis & Gene. The author has an hindex of 8, co-authored 16 publications. Previous affiliations of Emma Carmelo include University of Manchester.
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Papers
The Unstructured N-terminal Tail of ParG Modulates Assembly of a Quaternary Nucleoprotein Complex in Transcription Repression
TL;DR: ParG as mentioned in this paper is the prototype of a group of small (<10 kDa) proteins involved in accurate plasmid segregation, which consists of symmetric paired C-terminal domains that interleave into a ribbon-helixhelix fold that is crucial for the interaction with DNA.
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Transcriptional Profiling of Immune-Related Genes in Leishmania infantum-Infected Mice: Identification of Potential Biomarkers of Infection and Progression of Disease
Eduardo Ontoria,Yasmina E. Hernandez-Santana,Ana C. Gonzalez-García,Manuel Carlos López,Basilio Valladares,Emma Carmelo +5 more
TL;DR: In this article, a large-scale analysis of 112 immune-related genes has been analyzed using high-throughput qPCR in spleens of infected and naive Balb/c mice at four different time points.
Analysis of NLS and rRNA binding motifs in the L25 ribosomal protein from Leishmania (viannia) braziliensis: investigation of its diagnostic capabilities.
Ana C. González,E. Martinez,Emma Carmelo,José E. Piñero,V. Alonso,A. del Castillo,Basilio Valladares +6 more
TL;DR: The results indicate that the recombinant RPL25 from L. braziliensis presents a non-specific reaction that disqualifies it for the diagnosis of cutaneous leishmaniasis, in contrast, some of the synthetic peptides derived from its sequence may serve as promising tools for the diagnosed of this disease.
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Antigenicity of Leishmania braziliensis Histone H1 during Cutaneous Leishmaniasis: Localization of Antigenic Determinants
Emma Carmelo,E. Martinez,Ana C. González,José E. Piñero,Manuel E. Patarroyo,Antonio Rodriguez del Castillo,Basilio Valladares +6 more
TL;DR: The results show that the recombinant L. braziliensis histone H1 is recognized by a significant percentage of serum samples from patients with cutaneous leishmaniasis, but use of this protein as a tool for the diagnosis of cutaneousLeishmanniasis is hampered by the cross-reaction with sera from patientswith Chagas' disease.
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Cloning and Molecular Characterization of the cDNA Encoding Histone H1 From Leishmania braziliensis
E. Martinez,María del Carmen Thomas,V. Alonso,Emma Carmelo,Ana C. González,A. del Castillo,Basilio Valladares +6 more
TL;DR: The isolation and molecular characterization of the histone H1-encoding gene from Leishmania braziliensis was carried out and the deduced amino acid sequence has in its central region the DNA binding K-[K/R]-A-A-[A/P] motif, which is repeated in tandem 9 times.
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