Ellen Donnert
Vanderbilt University Medical Center
5 Papers
120 Citations
Ellen Donnert is an academic researcher from Vanderbilt University Medical Center. The author has contributed to research in topics: Glomerulosclerosis & Internal medicine. The author has an hindex of 5, co-authored 5 publications. Previous affiliations of Ellen Donnert include Vanderbilt University.
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Papers
Proteomic Patterns and Prediction of Glomerulosclerosis and Its Mechanisms
Baogang J. Xu,Yu Shyr,Xiubin Liang,Li-Jun Ma,Ellen Donnert,Jeremy D. Roberts,Xueqiong Zhang,Valentina Kon,Nancy J. Brown,Richard M. Caprioli,Agnes B. Fogo +10 more
TL;DR: Protein expression profiles linked to sclerosis in the 5/6 nephrectomy (Nx) rat model of focal segmental glomerulosclerosis suggest early activation of prosclerotic mechanisms even in seemingly intact glomeruli and thymosin beta4 is a marker of such early events and may even contribute to sclerosis.
Sulodexide ameliorates early but not late kidney disease in models of radiation nephropathy and diabetic nephropathy
Michele Rossini,Takashi Naito,Haichun Yang,Michael R. Freeman,Ellen Donnert,Li-Jun Ma,Stephen R. Dunn,Kumar Sharma,Agnes B. Fogo +8 more
TL;DR: The data show that sulodexide can reduce the early, but not late, proteinuria in radiation nephropathy in rats and did not affect urine TGF-beta established albuminuria or mesangial matrix expansion in a chronic model of diabetic kidney disease in mice.
Increased Capillary Branching Contributes to Angiotensin Type 1 Receptor Blocker (ARB)–Induced Regression of Sclerosis
TL;DR: The theory that capillary growth contributes to regression of sclerosis and is mediated at least in part by ARB-induced increased complexity and branching of capillary segments is supported.
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Aldosterone modulates plasminogen activator inhibitor-1 and glomerulosclerosis in vivo
Nancy J. Brown,Shinya Nakamura,Li-Jun Ma,Ikuko Nakamura,Ellen Donnert,Michael L. Freeman,Douglas E. Vaughan,Agnes B. Fogo +7 more
TL;DR: This study is, to the authors' knowledge, the first to demonstrate that aldosterone regulates PAI-1 expression in vivo, and supports the hypothesis that a Aldosterone induces renal injury through its effects on PAI/GAPDH expression.
Immunolocalization of fibroblast growth factor-1 (FGF-1), its receptor (FGFR-1), and fibroblast-specific protein-1 (FSP-1) in inflammatory renal disease
Michele Rossini,Boonyarit Cheunsuchon,Ellen Donnert,Li-Jun Ma,James W. Thomas,Eric G. Neilson,Agnes B. Fogo +6 more
TL;DR: The expression of FGF-1 and FGFR-1 in infiltrating lymphocytes and macrophages, and of FGFR -1 in tubules, is supportive, but does not prove causality, of the possibility that F GF-1 might have both autocrine and paracrine functions in renal inflammation.