Elisabetta Rubini
Sapienza University of Rome
11 Papers
43 Citations
Elisabetta Rubini is an academic researcher from Sapienza University of Rome. The author has contributed to research in topics: Chemistry & Biology. The author has an hindex of 4, co-authored 8 publications. Previous affiliations of Elisabetta Rubini include Université libre de Bruxelles.
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Papers
ERp57/PDIA3: new insight
Silvia Chichiarelli,Fabio Altieri,Giuliano Paglia,Elisabetta Rubini,M Minacori,Margherita Eufemi +5 more
TL;DR: The ERp57/PDIA3 protein is a pleiotropic member of the PDIs family and although predominantly located in the endoplasmic reticulum (ER), has indeed been found in other cellular compartments, such as the nucleus or the cell membrane as mentioned in this paper .
STAT3 Post-Translational Modifications Drive Cellular Signaling Pathways in Prostate Cancer Cells.
Rossana Cocchiola,Elisabetta Rubini,Fabio Altieri,Silvia Chichiarelli,Giuliano Paglia,Donatella Romaniello,Stefania Carissimi,Alessandra Giorgi,Flavia Giamogante,Alberto Macone,Giacomo Perugia,Aymone Gurtner,Margherita Eufemi +12 more
TL;DR: Assessment of the correspondence between the stimulus-specificity of STAT3 PTMs and definite STAT3-mediated transcriptional programs, in order to identify new suitable pharmacological targets for PCa treatment, highlighted the role ofSTAT3 and its PTMs as drivers in the progression of PCa.
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Modulation of STAT3 Signaling, Cell Redox Defenses and Cell Cycle Checkpoints by β-Caryophyllene in Cholangiocarcinoma Cells: Possible Mechanisms Accounting for Doxorubicin Chemosensitization and Chemoprevention.
Antonella Di Sotto,Silvia Di Giacomo,Elisabetta Rubini,Alberto Macone,Marco Gullì,Caterina Loredana Mammola,Margherita Eufemi,Romina Mancinelli,Gabriela Mazzanti +8 more
TL;DR: Evidence highlighted a possible role of STAT3 as a final effector of a complex network regulated by β-caryophyllene, which leads to an enhanced doxorubicin-sensitivity of cholangiocarcinoma cells and a lowered chemotherapy toxicity in nonmalignant cholangsiocytes, thus strengthening the interest for this natural sesquiterpene as a dual-acting chemosensitizing and chemopreventive agent.
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β-Hexachlorocyclohexane: A Small Molecule with a Big Impact on Human Cellular Biochemistry
Elisabetta Rubini,Elisabetta Rubini,Giuliano Paglia,David Cannella,Alberto Macone,Antonella Di Sotto,Marco Gullì,Fabio Altieri,Margherita Eufemi +8 more
TL;DR: The hypothesis that β-HCH could be an endocrine disrupting chemical as well as an activator of AhR signaling, promoting the establishment of an oxidative stress condition and a cellular metabolic shift toward aerobic glycolysis is strongly supported.
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ERp57/PDIA3: new insight
Silvia Chichiarelli,Fabio Altieri,Giuliano Paglia,Elisabetta Rubini,M Minacori,Margherita Eufemi +5 more
TL;DR: The ERp57/PDIA3 protein is a pleiotropic member of the PDIs family and although predominantly located in the endoplasmic reticulum (ER), has indeed been found in other cellular compartments, such as the nucleus or the cell membrane as discussed by the authors .