Elif Arioglu
National Institutes of Health
13 Papers
97 Citations
Elif Arioglu is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Insulin resistance & Lipodystrophy. The author has an hindex of 11, co-authored 13 publications. Previous affiliations of Elif Arioglu include University of Texas Southwestern Medical Center.
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Papers
AGPAT2 is mutated in congenital generalized lipodystrophy linked to chromosome 9q34.
Anil K. Agarwal,Elif Arioglu,Salome De Almeida,Nurullah Akkoc,Simeon I. Taylor,Anne M. Bowcock,Robert Barnes,Abhimanyu Garg +7 more
TL;DR: It is concluded that mutations in AGPAT2 may cause congenital generalized lipodystrophy by inhibiting triacylglycerol synthesis and storage in adipocytes.
Mutational and haplotype analyses of families with familial partial lipodystrophy (Dunnigan variety) reveal recurrent missense mutations in the globular C-terminal domain of lamin A/C.
Rebecca A. Speckman,Abhimanyu Garg,Fenghe Du,Lynda Bennett,Rose Veile,Elif Arioglu,Simeon I. Taylor,Michael Lovett,Anne M. Bowcock +8 more
TL;DR: The FPLD mutations R482Q and R482W occurred on different haplotypes, indicating that they are likely to have arisen more than once, and mutations responsible for dilated cardiomyopathy and conduction-system disease are observed in the rod domain of the protein.
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A gene for congenital generalized lipodystrophy maps to human chromosome 9q34.
Abhimanyu Garg,Ross Wilson,Robert Barnes,Elif Arioglu,Zohra Zaidi,Figen Gürakan,Nurten Koçak,Stephen O'Rahilly,Simeon I. Taylor,Shailendra B. Patel,Anne M. Bowcock,Anne M. Bowcock +11 more
TL;DR: A semi-automated genome-wide scan with a set of highly polymorphic short tandem repeats was carried out and identified a locus for CGL to chromosome 9q34 that harbors a plausible candidate gene encoding the retinoid X receptor alpha (RXRA) that plays a central role in adipocyte differentiation.
Cushing's Syndrome Caused by Corticotropin Secretion by Pulmonary Tumorlets
Elif Arioglu,John L. Doppman,Mario N. Gomes,David E. Kleiner,David Mauro,Carolee Barlow,Dimitris A. Papanicolaou +6 more
TL;DR: This work describes a patient with Cushing's syndrome due to ectopic secretion of corticotropin in whom the source of the excess corticotropic secretion was ultimately found to be hundreds of tumorlets in one lobe of the lung.
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