Eliezer Masliah
National Institutes of Health
1018 Papers
7.3K Citations
Eliezer Masliah is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Neurodegeneration & Biology. The author has an hindex of 170, co-authored 982 publications. Previous affiliations of Eliezer Masliah include University of Miami & Scripps Research Institute.
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Papers
Dual effects of β-synuclein on the pathogenesis of Parkinson disease.
Akio Sekigawa,Kazunari Sekiyama,Masayo Fujita,Yoshiki Takamatsu,Albert R. La Spada,Albert R. La Spada,Eliezer Masliah,Makoto Hashimoto +7 more
TL;DR: The results of Taschenberger and colleagues suggest that aggregation of wild-type b-syn might be involved in neurodegeneration in sporadic cases of Parkinson disease and other a-synucleinopathies.
Methamphetamine: A molecular and pathological exacerbate of HIV neurocognitive disorder
TL;DR: Molecular research indicates that methamphetamine and HIV have a synergistic pathological impact on neuronal cell injury and death, which may be mediated by an upregulation of interferon inducible genes observed within this group, thereby contributing to the neurocognitive deficits observed in clinical populations of HIV infected methamphetamine abusers.
Impact of α‐synuclein RNA interference on Neuropathological and Clinical Phenotypes in a mouse model of Alzheimer’s Disease
André D. G. Leitão,Brian Spencer,Chengbiao Wu,Abigail Conroy,Jessica Amalraj,Michael N Mante,Eliezer Masliah,Robert A. Rissman +7 more
TL;DR: In this paper , the role of α-synuclein has been extensively studied in Parkinson's disease, but less so in AD, and the authors hypothesized that selectively knocking down α−syn improves the neuropathological, biochemical, and cognitive findings in AD.
A unified hypothesis for the histogenesis of the soft tissue sarcomas of unknown origin
TL;DR: It is proposed that the common progenitor of these malignancies is an ectomesenchymal derived tissue related to the tendons, aponeuroses, synovia and menisci called chondroid tissue or pseudocartilage; the evolutionary reasons that support this hypothesis are also discussed here.
Patent
Transgenic mice for screening for inhibitors of protein aggregation and methods for making and using them
Eliezer Masliah,Edward Rockenstein,Makoto Hashimoto +2 more
- 15 Feb 2007
TL;DR: In this article, a critical balance between pro-and anti-amyloidogenic molecules exists that regulates amyloid formation and cell death in Alzheimer's disease and Parkinson's disease.