Eleni Dimou
Heidelberg University
20 Papers
19 Citations
Eleni Dimou is an academic researcher from Heidelberg University. The author has contributed to research in topics: Secretion & Chemistry. The author has an hindex of 11, co-authored 16 publications. Previous affiliations of Eleni Dimou include Aristotle University of Thessaloniki & University of Cambridge.
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Papers
Unconventional Secretion Mediates the Trans-cellular Spreading of Tau.
Taxiarchis Katsinelos,Marcel Zeitler,Eleni Dimou,Andromachi Karakatsani,Hans-Michael Müller,Eliana Nachman,Eliana Nachman,Julia P. Steringer,Carmen Ruiz de Almodovar,Walter Nickel,Thomas R. Jahn +10 more
TL;DR: This study shows that full-length soluble tau is unconventionally secreted by direct translocation across the plasma membrane and provides insights into the initiation and progression of tau pathology.
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Unconventional mechanisms of eukaryotic protein secretion
Eleni Dimou,Walter Nickel +1 more
TL;DR: The mechanisms and molecular machineries of these pathways that were discovered with fibroblast growth factor 2 and acyl-CoA binding protein (Acb1; type III) as the most prominent cargo proteins are highlighted.
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Combination of diclofenac plus somatostatin in the prevention of post-ERCP pancreatitis: a randomized, double-blind, placebo-controlled trial
Panagiotis Katsinelos,Kostas Fasoulas,George Paroutoglou,Grigoris Chatzimavroudis,Athanasios Beltsis,Sotiris Terzoudis,Taxiarchis Katsinelos,Eleni Dimou,Christos Zavos,Agoritsa Kaltsa,Jannis Kountouras +10 more
TL;DR: Combined prophylactic therapy with diclofenac plus somatostatin was promising in reducing frequency of post-ERCP pancreatitis, but further comparative large-scale studies are needed to confirm the findings before definitive conclusions can be drawn.
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Formation of Disulfide Bridges Drives Oligomerization, Membrane Pore Formation and Translocation of Fibroblast Growth Factor 2 to Cell Surfaces
Hans-Michael Müller,Julia P. Steringer,Sabine Wegehingel,Stephanie Bleicken,Maximilian Münster,Eleni Dimou,Sebastian Unger,Georg Weidmann,Helena Andreas,Ana J. García-Sáez,Ana J. García-Sáez,Klemens Wild,Irmgard Sinning,Walter Nickel +13 more
TL;DR: It is shown that phosphatidylinositol 4,5-bisphosphate-dependent FGF2 oligomerization concomitant with the generation of membrane pores depends on F GF2 surface cysteines as either chemical alkylation or substitution with alanines impairs these processes.
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A direct role for ATP1A1 in unconventional secretion of fibroblast growth factor 2.
Sonja Zacherl,Giuseppe La Venuta,Hans-Michael Müller,Sabine Wegehingel,Eleni Dimou,Peter Sehr,Joe Lewis,Holger Erfle,Rainer Pepperkok,Walter Nickel +9 more
TL;DR: It is proposed that ATP1A1 is a recruitment factor for FGF2 at the inner leaflet of plasma membranes that may control phosphatidylinositol 4,5-bisphosphate-dependent membrane translocation as part of the unconventional secretory pathway of F GF2.
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