Elena M. Silva
Georgetown University
7 Papers
Elena M. Silva is an academic researcher from Georgetown University. The author has contributed to research in topics: Neurogenesis & Neural plate. The author has an hindex of 4, co-authored 7 publications.
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Papers
The role of targeted protein degradation in early neural development
TL;DR: The studies show that targeted protein degradation is an important regulatory mechanism in the generation of new neurons in neural stem cells during neurogenesis.
Stable intronic sequence RNAs (sisRNAs) are selected regions in introns with distinct properties
TL;DR: The results indicate sisRNAs are selected intron regions with distinct properties and may play a role in gene expression regulation and Evolutionary conservation analysis of sisRNA sequences in seven vertebrate genomes indicates that sis RNAs are as conserved as other parts of introns, but much less conserved than exons.
4
Pairing your Sox: identification of Sox11 partner proteins and interaction domains in the developing neural plate
TL;DR: This is the first identification of partner proteins and the domains of Xenopus Sox11(xSox11) required for protein interaction and function during neurogenesis and established a novel role for the N-terminal 46 amino acids in the establishment of placodal progenitors.
Genome-Wide Identification and Expression of Xenopus F-Box Family of Proteins.
TL;DR: This work used a bioinformatics screen and phylogenetic analysis to identify and annotate the family of F-box proteins in the Xenopus tropicalis genome and shed light on the function of the F-boxes.
Cross-species functional analyses reveal shared and separate roles for Sox11 in frog primary neurogenesis and mouse cortical neuronal differentiation
TL;DR: Data show evolutionary conservation of Sox11 function with molecular divergence, which is species-specific in frog neural development and mouse corticogenesis and acts to designate neurons in both mouse and frog brains, but orthologs are not functionally redundant.