Eleanor J. Mackie
University of Melbourne
133 Papers
1.9K Citations
Eleanor J. Mackie is an academic researcher from University of Melbourne. The author has contributed to research in topics: Tenascin & Tenascin C. The author has an hindex of 48, co-authored 132 publications. Previous affiliations of Eleanor J. Mackie include Australian National University & University of Helsinki.
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Papers
Osteopontin, inflammation and myogenesis: influencing regeneration, fibrosis and size of skeletal muscle.
TL;DR: Osteopontin is a multifunctional matricellular protein that is expressed by many cell types as mentioned in this paper, and it has been found to be involved in important physiological and pathological processes, including tissue repair, inflammation and fibrosis.
Tenascin expression in hyperproliferative skin diseases.
J. Schalkwijk,I. M. J. J. Van Vlijmen,B Oosterling,C. M. Perret,R Koopman,J Van den Born,Eleanor J. Mackie +6 more
TL;DR: The expression of tenascin, a recently discovered extracellular matrix glycoprotein, was studied by immunohistochemistry in normal human skin and in a number of skin diseases with epidermal hyperproliferation such as psoriasis, basal cell carcinoma, Bowen's disease and solar keratosis.
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EphrinB2 signaling in osteoblasts promotes bone mineralization by preventing apoptosis
Stephen Tonna,Farzin M. Takyar,Christina Vrahnas,Blessing Crimeen-Irwin,Patricia W. M. Ho,Ingrid J Poulton,Holly J. Brennan,Narelle E. McGregor,E H Allan,Huynh Nguyen,Mark R. Forwood,Liliana Tatarczuch,Eleanor J. Mackie,T. John Martin,Natalie A. Sims +14 more
TL;DR: Osteoblast differentiation and bone strength are maintained by antiapoptotic actions of ephrinB2 signaling within the osteoblast lineage, which promotes bone mineralization by preventing apoptosis.
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Modulation of osteoblast behaviour by tenascin
Eleanor J. Mackie,S Ramsey +1 more
TL;DR: The results presented here indicate that tenascin is able to stimulate osteoblastic differentiation and that endogenousTenascin helps to maintain the functional state of cultured osteoblast-like cells.
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•Journal Article
Tenascin expression in human dermis is related to epidermal proliferation.
J. Schalkwijk,Peter M. Steijlen,I.M.J.J. van Vlijmen-Willems,B Oosterling,Eleanor J. Mackie,A.A. Verstraeten +5 more
TL;DR: Findings demonstrate a relationship between epidermal proliferation and metabolic alterations in the dermal compartment and test the hypothesis that tenascin expression in vivo is linked to epidersmal proliferation.
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