Elad I. Levy
University at Buffalo
799 Papers
4.1K Citations
Elad I. Levy is an academic researcher from University at Buffalo. The author has contributed to research in topics: Medicine & Stroke. The author has an hindex of 73, co-authored 613 publications. Previous affiliations of Elad I. Levy include Boston Children's Hospital & Kaleida Health.
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Papers
Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials
Mayank Goyal,Bijoy K Menon,Wim H. van Zwam,Diederik W.J. Dippel,Peter Mitchell,Andrew M. Demchuk,Antoni Dávalos,Charles B. L. M. Majoie,Aad van der Lugt,Maria Angeles De Miquel,Geoffrey A. Donnan,Yvo B.W.E.M. Roos,Alain Bonafe,Reza Jahan,Hans-Christoph Diener,Lucie A. van den Berg,Elad I. Levy,Olvert A. Berkhemer,Vitor Mendes Pereira,Jeremy L. Rempel,Mónica Millán,Stephen M. Davis,Daniel Roy,John Thornton,Luis San Roman,Marc Ribo,Debbie Beumer,Bruce Stouch,Scott Brown,Bruce C.V. Campbell,Robert J. van Oostenbrugge,Jeffrey L. Saver,Michael D. Hill,Tudor G Jovin +33 more
TL;DR: Endovascular thrombectomy is of benefit to most patients with acute ischaemic stroke caused by occlusion of the proximal anterior circulation, irrespective of patient characteristics or geographical location, and will have global implications on structuring systems of care to provide timely treatment.
6.5K
Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke
Jeffrey L. Saver,Mayank Goyal,Alain Bonafe,Hans-Christoph Diener,Elad I. Levy,Vitor Mendes Pereira,Gregory W. Albers,Christophe Cognard,David J. Cohen,Werner Hacke,Olav Jansen,Tudor G Jovin,Heinrich Mattle,Raul G Nogueira,Adnan H. Siddiqui,Dileep R. Yavagal,Blaise Baxter,Thomas Devlin,Demetrius K. Lopes,Vivek Y. Reddy,Richard du Mesnil de Rochemont,Oliver C. Singer,Reza Jahan +22 more
TL;DR: In patients receiving intravenous t-PA for acute ischemic stroke, thrombectomy with the use of a stent retriever within 6 hours after onset improved functional outcomes at 90 days.
Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct.
Raul G Nogueira,Ashutosh P Jadhav,Diogo C Haussen,Alain Bonafe,Ronald F. Budzik,Parita Bhuva,Dileep R. Yavagal,Marc Ribo,Christophe Cognard,Ricardo A. Hanel,Cathy A. Sila,Ameer E Hassan,Mónica Millán,Elad I. Levy,Peter Mitchell,Michael Chen,Joey English,Qaisar A. Shah,Frank L. Silver,Vitor Mendes Pereira,Brijesh P Mehta,Blaise Baxter,Michael G. Abraham,Pedro Cardona,Erol Veznedaroglu,Frank R Hellinger,Lei Feng,Jawad F. Kirmani,Demetrius K. Lopes,Brian T. Jankowitz,Michael Frankel,Vincent Costalat,Nirav Vora,Albert J Yoo,Amer M. Malik,Anthony J. Furlan,Marta Rubiera,Amin Aghaebrahim,Jean-Marc Olivot,Wondwossen G Tekle,Ryan K. Shields,Todd Graves,Roger J. Lewis,Wade S. Smith,David S Liebeskind,Jeffrey L. Saver,Tudor G Jovin +46 more
TL;DR: Among patients with acute stroke who had last been known to be well 6 to 24 hours earlier and who had a mismatch between clinical deficit and infarct, outcomes for disability at 90 days were better with thrombectomy plus standard care than with standard care alone.
4.5K
Stenting versus Aggressive Medical Therapy for Intracranial Arterial Stenosis
Marc I. Chimowitz,Michael J. Lynn,Colin P. Derdeyn,Tanya N. Turan,David Fiorella,Bethany F Lane,L. Scott Janis,Helmi L. Lutsep,Stanley L. Barnwell,Michael F. Waters,Brian L. Hoh,J. Maurice Hourihane,Elad I. Levy,Andrei V. Alexandrov,Mark R. Harrigan,David Chiu,Richard P. Klucznik,Joni Clark,Cameron G. McDougall,Mark D. Johnson,G. Lee Pride,Michel T. Torbey,Osama O. Zaidat,Zoran Rumboldt,Harry J. Cloft +24 more
TL;DR: In patients with intracranial arterial stenosis, aggressive medical management was superior to PTAS with the use of the Wingspan stent system, both because the risk of early stroke after PTAS was high and because therisk of stroke with aggressive medical therapy alone was lower than expected.
Pipeline for Uncoilable or Failed aneurysms: Results from a
Tibor Becske,David F. Kallmes,Isil Saatci,Cameron G. McDougall,István Szikora,Giuseppe Lanzino,Chris Moran,Henry H. Woo,Demetrius K. Lopes,Aaron L. Berez,Daniel J. Cher,Adnan H. Siddiqui,Elad I. Levy,Felipe C. Albuquerque,David Fiorella,Zsolt Berentei,Saruhan Cekirge,Peter Kim Nelson +17 more
- 01 Jan 2013
Abstract: PURPOSE
To evaluate the safety and effectiveness of the Pipeline Embolization Device (PED; ev3/Covidien, Irvine, Calif) in the treatment of complex intracranial aneurysms.
MATERIALS AND METHODS
The Pipeline for Uncoilable or Failed Aneurysms is a multicenter, prospective, interventional, single-arm trial of PED for the treatment of uncoilable or failed aneurysms of the internal carotid artery. Institutional review board approval of the HIPAA-compliant study protocol was obtained from each center. After providing informed consent, 108 patients with recently unruptured large and giant wide-necked aneurysms were enrolled in the study. The primary effectiveness endpoint was angiographic evaluation that demonstrated complete aneurysm occlusion and absence of major stenosis at 180 days. The primary safety endpoint was occurrence of major ipsilateral stroke or neurologic death at 180 days.
RESULTS
PED placement was technically successful in 107 of 108 patients (99.1%). Mean aneurysm size was 18.2 mm; 22 aneurysms (20.4%) were giant (>25 mm). Of the 106 aneurysms, 78 met the study's primary effectiveness endpoint (73.6%; 95% posterior probability interval: 64.4%-81.0%). Six of the 107 patients in the safety cohort experienced a major ipsilateral stroke or neurologic death (5.6%; 95% posterior probability interval: 2.6%-11.7%).
CONCLUSION
PED offers a reasonably safe and effective treatment of large or giant intracranial internal carotid artery aneurysms, demonstrated by high rates of complete aneurysm occlusion and low rates of adverse neurologic events; even in aneurysms failing previous alternative treatments.
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