Ekhtiar Rahman
University of Rajshahi
10 Papers
8 Citations
Ekhtiar Rahman is an academic researcher from University of Rajshahi. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 4, co-authored 5 publications.
Chat about Author
Papers
Virtual screening and molecular dynamics simulation study of plant-derived compounds to identify potential inhibitors of main protease from SARS-CoV-2.
Shafi Mahmud,Mohammad Abu Raihan Uddin,Gobindo Kumar Paul,Mst Sharmin Sultana Shimu,Saiful Islam,Ekhtiar Rahman,Ariful Islam,Samiul Islam,Maria Meha Promi,Talha Bin Emran,Talha Bin Emran,Abu Saleh +11 more
TL;DR: In this paper, the authors employed a rigorous literature review pipeline to enlist 3063 compounds from more than 200 plants from the Asian region and employed a virtual screening procedure to shortlist the total compounds into 19 based on their better binding energy.
Molecular docking and dynamics study of natural compound for potential inhibition of main protease of SARS-CoV-2.
Shafi Mahmud,Mohammad Abu Raihan Uddin,Meemtaheena Zaman,Khaled Mahmud Sujon,Ekhtiar Rahman,Mobasshir Noor Shehab,Ariful Islam,Wasim Alom,Al Amin,Al Shahriar Akash,Abu Saleh +10 more
TL;DR: This study presents a perfect model for SARS-CoV-2 main protease inhibition through bioinformatics study and considers plant-derived natural compounds as potential drug candidates to assist the researchers to find a superior and effective solution against COVID-19 after future experiments.
48
Comparative molecular investigation of the potential inhibitors against SARS-CoV-2 main protease: a molecular docking study.
Arif Khan,Shafi Mahmud,A. S. M. Rubayet Ul Alam,Ekhtiar Rahman,Firoz Ahmed,Mohammed Rahmatullah +5 more
TL;DR: The overall prediction findings indicate that Epirubicin, Vapreotida, and Saquinavir may inhibit COVID-19 by synergistic interactions in the active cavity and those results can pave the way in drug discovery although it has to be further validated by in-vitro and in- vivo investigations.
39
Computational discovery of plant-based inhibitors against human carbonic anhydrase IX and molecular dynamics simulation
Shafi Mahmud,Ekhtiar Rahman,Zulkar Nain,Mutasim Billah,Sumon Karmakar,Sumon Chandro Mohanto,Gobindo Kumar Paul,Al Amin,Uzzal Kumar Acharjee,Md. Abu Saleh +9 more
TL;DR: Analysis of protein-protein interactions and co-expression revealed the possible association of CA9 gene with other tumorous genes, especially angiogenesis factor HIF1A which will most likely be affected by the identified inhibitors.
36
phytochemdb: a platform for virtual screening and computer-aided drug designing
Shafi Mahmud,Gobindo Kumar Paul,Suvro Biswas,Taheruzzaman Kazi,Shafquat Mahbub,Mohasana Akter Mita,Shamima Afrose,Ariful Islam,Sheikh Ahaduzzaman,Md. Robiul Hasan,Sharmin Sultana Shimu,Maria Meha Promi,Mobasshir Noor Shehab,Ekhtiar Rahman,Khaled Mahmud Sujon,Md Wasim Alom,Anik Modak,Shahriar Zaman,Md. Salah Uddin,Talha Bin Emran,Md. Sayeedul Islam,Md. Abu Saleh +21 more
TL;DR: Phytochemdb as mentioned in this paper is a manually managed database that compiles 525 plants and their corresponding 8093 phytochemicals, aiming to incorporate the activities of PHYochemicals from medicinal plants.
29