Eileen Nugent
University of Cambridge
6 Papers
7 Citations
Eileen Nugent is an academic researcher from University of Cambridge. The author has contributed to research in topics: Population & Biology. The author has an hindex of 5, co-authored 5 publications.
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Papers
Inflammasome activation causes dual recruitment of NLRC4 and NLRP3 to the same macromolecular complex
Si Ming Man,Lee Hopkins,Eileen Nugent,Susan Cox,Ivo M. Glück,Panagiotis Tourlomousis,John A. Wright,Pietro Cicuta,Tom P. Monie,Clare E. Bryant +9 more
TL;DR: The data reveal the spatial localization of different components of the inflammasome and how different members of the NLR family cooperate to drive robust IL-1β processing within the Salmonella-infected cell and to regulate the bacterial burden in mice.
Concerted control of Escherichia coli cell division
TL;DR: This work introduces a quantitative method for estimating the variables controlling division rate and uses it to construct a minimal model from large-scale dynamic data on the size of dividing Escherichia coli cells, and quantifies cell division control using a stochastic model.
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Super-resolution imaging of alpha-synuclein polymorphisms and their potential role in neurodegeneration.
TL;DR: This mini review will discuss structural polymorphisms of α-synuclein, as determined by super-resolution imaging techniques, and how these may be related to neuronal toxicity.
Microfluidic chemostat for measuring single cell dynamics in bacteria
Zhicheng Long,Eileen Nugent,Avelino Javer,Pietro Cicuta,Bianca Sclavi,Marco Cosentino Lagomarsino,Marco Cosentino Lagomarsino,Kevin D. Dorfman +7 more
TL;DR: A microfluidic chemostat consisting of 600 sub-micron trapping/growth channels connected to two feeding channels is designed and demonstrated by tracking with sub-diffraction resolution the movements of fluorescently tagged loci in more than one thousand cells on a single device.