Efrain Ribeiro
Icahn School of Medicine at Mount Sinai
14 Papers
19 Citations
Efrain Ribeiro is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Nucleus accumbens & Ventral tegmental area. The author has an hindex of 10, co-authored 14 publications. Previous affiliations of Efrain Ribeiro include Wesleyan University & Allen Institute for Brain Science.
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Papers
Dopaminergic dynamics underlying sex-specific cocaine reward.
Erin S. Calipari,Barbara Juarez,Carole Morel,Deena M. Walker,Michael E. Cahill,Efrain Ribeiro,Ciorana Roman-Ortiz,Charu Ramakrishnan,Karl Deisseroth,Ming-Hu Han,Eric J. Nestler +10 more
TL;DR: An oestrous cycle-dependent mechanism controlling increased cocaine reward in females is demonstrated and a mechanism by which cellular activity results in protein alterations that contribute to dysfunctional learning and reward processing is defined.
Alterations of the Host Microbiome Affect Behavioral Responses to Cocaine
Drew D. Kiraly,Deena M. Walker,Erin S. Calipari,Benoit Labonté,Orna Issler,Catherine Jensen Pena,Efrain Ribeiro,Scott J. Russo,Eric J. Nestler +8 more
TL;DR: This study presents the first evidence that alterations in the gut microbiota affect behavioral response to drugs of abuse, and shows animals with reduced gut bacteria showed an enhanced sensitivity to cocaine reward and enhancedensitivity to the locomotor-sensitizing effects of repeated cocaine administration.
β-catenin mediates stress resilience through Dicer1/microRNA regulation
Caroline Dias,Jian Feng,HaoSheng Sun,Ning Y.i. Shao,Michelle S. Mazei-Robison,Diane M. Damez-Werno,Kimberly N. Scobie,Rosemary C. Bagot,Benoit Labonté,Efrain Ribeiro,Xiaochuan Liu,Pamela J. Kennedy,Vincent Vialou,Deveroux Ferguson,Catherine Jensen Pena,Erin S. Calipari,Ja W.ook Koo,Ezekiell Mouzon,Subroto Ghose,Carol A. Tamminga,Rachael L. Neve,Li Shen,Eric J. Nestler +22 more
TL;DR: The authors showed that β-catenin mediates proresilient and anxiolytic effects in the nucleus accumbens, a key brain reward region, an effect mediated by D2-type medium spiny neurons.
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Epigenetic basis of opiate suppression of Bdnf gene expression in the ventral tegmental area
Ja Wook Koo,Michelle S. Mazei-Robison,Quincey LaPlant,Gabor Egervari,Kevin M Braunscheidel,Danielle N. Adank,Deveroux Ferguson,Jian Feng,HaoSheng Sun,Kimberly N. Scobie,Diane M. Damez-Werno,Efrain Ribeiro,Catherine Jensen Pena,Deena M. Walker,Rosemary C. Bagot,Michael E. Cahill,Sarah Ann R. Anderson,Benoit Labonté,Georgia E. Hodes,Heidi A. Browne,Benjamin Chadwick,Alfred J. Robison,Vincent Vialou,Caroline Dias,Zachary S. Lorsch,Ezekiell Mouzon,Mary Kay Lobo,David M. Dietz,Scott J. Russo,Rachael L. Neve,Yasmin L. Hurd,Eric J. Nestler +31 more
TL;DR: It is found that morphine suppressed binding of phospho-CREB (cAMP response element binding protein) to Bdnf promoters in VTA, which resulted from enrichment of trimethylated H3K27 at the promoters, and that decreased NURR1 (nuclear receptor related-1) expression also contributed to BDNf repression and associated behavioral plasticity to morphine.
Midbrain circuit regulation of individual alcohol drinking behaviors in mice.
Barbara Juarez,Carole Morel,Stacy M. Ku,Yutong Liu,Hongxing Zhang,Hongxing Zhang,Sarah E. Montgomery,Hilledna Gregoire,Efrain Ribeiro,Marshall Crumiller,Ciorana Roman-Ortiz,Jessica J. Walsh,Kelcy Jackson,Denise E. Croote,Yingbo Zhu,Song Zhang,Leandro F. Vendruscolo,Scott Edwards,Amanda J. Roberts,Georgia E. Hodes,Yongke Lu,Erin S. Calipari,Erin S. Calipari,Dipesh Chaudhury,Dipesh Chaudhury,Allyson K. Friedman,Allyson K. Friedman,Ming-Hu Han +27 more
TL;DR: It is shown that stimulating VTA neurons to induce higher phasic activity patterns that are observed in low alcohol drinking mice, suppresses alcohol drinking in mice that are high alcohol drinking.