Edward K. Wakeland
University of Texas Southwestern Medical Center
275 Papers
3.3K Citations
Edward K. Wakeland is an academic researcher from University of Texas Southwestern Medical Center. The author has contributed to research in topics: Lupus erythematosus & Gene. The author has an hindex of 74, co-authored 265 publications. Previous affiliations of Edward K. Wakeland include University of Texas at Dallas & Stanford University.
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Papers
Erratum: Personalized immunomonitoring uncovers molecular networks that stratify lupus patients ((Cell (2016) 165 (551-565))
Romain Banchereau,Seunghee Hong,Brandi L. Cantarel,Nicole Baldwin,Jeanine Baisch,Michelle Edens,Alma-Martina Cepika,Peter Acs,Jacob Turner,Esperanza Anguiano,Parvathi Vinod,Shaheen Khan,Gerlinde Obermoser,Derek Blankenship,Edward K. Wakeland,Lorien Nassi,Alisa Gotte,Marilynn Punaro,Yong-Jun Liu,Jacques Banchereau,Jose Rossello-Urgell,Tracey Wright,Virginia Pascual +22 more
TL;DR: This dissertation aims to provide a history of web exceptionalism from 1989 to 2002, a period chosen in order to explore its roots as well as specific cases up to and including the year in which descriptions of “Web 2.0” began to circulate.
The nature and identification of quantitative trait loci: a community's view.
Oduola Abiola,Joe M. Angel,Philip Avner,Alexander A. Bachmanov,John K. Belknap,Beth Bennett,Elizabeth P. Blankenhorn,David A. Blizard,Valerie J. Bolivar,Gudrun A. Brockmann,Kari J. Buck,Jean Francois Bureau,William L. Casley,Elissa J. Chesler,James M. Cheverud,Gary A. Churchill,Melloni N. Cook,John C. Crabbe,Wim E. Crusio,Ariel Darvasi,Gerald de Haan,Peter Demant,Rebecca W. Doerge,Rosemary W. Elliott,Charles R. Farber,Lorraine Flaherty,Jonathan Flint,Howard K. Gershenfeld,John P. Gibson,Jing Gu,Weikuan Gu,Heinz Himmelbauer,Robert Hitzemann,Hui-Chen Hsu,Kent W. Hunter,Fuad A. Iraqi,Ritsert C. Jansen,Thomas E. Johnson,Byron C. Jones,Gerd Kempermann,Frank Lammert,Lu Lu,Kenneth F. Manly,Douglas B. Matthews,Juan F. Medrano,Margarete Mehrabian,Guy Mittleman,Beverly A. Mock,Jeffrey S. Mogil,Xavier Montagutelli,Grant Morahan,John D. Mountz,Hiroki Nagase,Richard S. Nowakowski,Bruce F. O'Hara,Alexander V. Osadchuk,Beverly Paigen,Abraham A. Palmer,Jeremy L. Peirce,Daniel Pomp,Michael Rosemann,Glenn D. Rosen,Leonard C. Schalkwyk,Ze'ev Seltzer,Stephen H. Settle,Kazuhiro Shimomura,Siming Shou,James M. Sikela,Linda D. Siracusa,Jimmy L. Spearow,Cory Teuscher,David W. Threadgill,Linda A. Toth,A. A. Toye,Csaba Vadasz,Gary Van Zant,Edward K. Wakeland,Robert W. Williams,Huang-Ge Zhang,Fei Zou +79 more
TL;DR: This white paper by eighty members of the Complex Trait Consortium presents a community's view on the approaches and statistical analyses that are needed for the identification of genetic loci that determine quantitative traits.
Trex1 regulates lysosomal biogenesis and interferon-independent activation of antiviral genes
Maroof Hasan,James Koch,Dinesh Rakheja,Asit K. Pattnaik,James Brugarolas,Igor Dozmorov,Beth Levine,Beth Levine,Edward K. Wakeland,Min Ae Lee-Kirsch,Nan Yan +10 more
TL;DR: The data identify Trex1 as a regulator of lysosomal biogenesis and interferon-independent activation of antiviral genes and show that dysregulation ofLysosomes can elicit innate immune responses.
Genetic dissection of lupus pathogenesis: a recipe for nephrophilic autoantibodies
Chandra Mohan,Laurence Morel,Ping Yang,Hiroshi Watanabe,Byron P. Croker,Gary S. Gilkeson,Edward K. Wakeland +6 more
TL;DR: These findings lend strong support to a two-step epistatic model for the formation of pathogenic, nephrophilic autoantibodies in lupus.
Genetic dissection of systemic lupus erythematosus.
TL;DR: Linkage studies in humans suggest that at least some susceptibility genes mediating disease in lupus-prone mice may also contribute to susceptibility in humans.