Edward K. L. Chan
University of Florida
345 Papers
3.9K Citations
Edward K. L. Chan is an academic researcher from University of Florida. The author has contributed to research in topics: Autoantibody & Antibody. The author has an hindex of 80, co-authored 334 publications. Previous affiliations of Edward K. L. Chan include New York University & University of Southern California.
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Papers
The uses and misuses of multiplex autoantibody assays in systemic autoimmune rheumatic diseases.
TL;DR: Advantages and current problems in the use of multiplex immunoassays are discussed.
•Journal Article
Early endosome antigen. 1: An autoantigen associated with neurological diseases.
TL;DR: Diagnoses included: polyneuropathy, lower motor neuron disease, pigmented retinitis, seronegative polyarthritis, interstitial pulmonary fibrosis, Raynaud's phenomenon, Wegener's granulomatosis, and proteinuria.
44
Characterization and purification of lupus antigen La, and RNA-binding protein.
TL;DR: HeLa cell La antigen, an RNA-binding protein, was characterized by using two-dimensional gel electrophoresis and an in vitro translation product similar in size and antigenicity was identified.
43
Analyses of autoantibodies against tumor-associated antigens in patients with hepatocellular carcinoma
Takashi Himoto,Shigeki Kuriyama,Jianying Zhang,Edward K. L. Chan,Yasuhiko Kimura,Tsutomu Masaki,Naohito Uchida,Mikio Nishioka,Eng M. Tan +8 more
TL;DR: Autoantibodies against tumor-associated antigens such as insulin-like growth factor II mRNA-binding proteins (IMPs), p53, c-myc, and survivin were analyzed in patients with hepatocellular carcinoma, indicating that anti-TAAs seem to be supplementary serological markers for the diagnosis of HCC in AFP-negative cases.
43
SS-56, a novel cellular target of autoantibody responses in Sjögren syndrome and systemic lupus erythematosus
Odile Billaut-Mulot,Cécile Cocude,Vincent Kolesnitchenko,Marie-José Truong,Edward K. L. Chan,Eric Hachula,Xavier de la Tribonnière,André Capron,George M. Bahr +8 more
TL;DR: Interestingly, the incidence of antibodies to SS-56 was associated with visceral complications in SLE, and roughly half of the 17 SS or SLE patients with no detectable antibodies to SSA and SSB antigens presented measurable antibodies against recombinant SS- 56.