Edward A. Burton
University of Pittsburgh
89 Papers
791 Citations
Edward A. Burton is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Zebrafish & Substantia nigra. The author has an hindex of 34, co-authored 83 publications. Previous affiliations of Edward A. Burton include Queen Elizabeth Hospital Birmingham & University of Oxford.
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Papers
Zebrafish DJ-1 is evolutionarily conserved and expressed in dopaminergic neurons.
TL;DR: It is shown that zDJ-1 is very similar to human DJ-1 and delineate essential resources, allowing further examination of the function and regulation of DJs-1, using the zebrafish as a model.
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Regeneration of the zebrafish retinal pigment epithelium after widespread genetic ablation.
Nicholas J. Hanovice,Lyndsay L. Leach,Kayleigh Slater,Ana E. Gabriel,Dwight K. Romanovicz,Enhua Shao,Enhua Shao,Ross F Collery,Edward A. Burton,Edward A. Burton,Kira L. Lathrop,Brian A. Link,Jeffrey M. Gross +12 more
TL;DR: It is demonstrated for the first time that zebrafish are capable of regenerating a functional RPE monolayer after RPE ablation, and a potential mechanism through which endogenous RPE regenerate in vivo is highlighted.
Soluble V Domain of Nectin-1/HveC Enables Entry of Herpes Simplex Virus Type 1 (HSV-1) into HSV-Resistant Cells by Binding to Viral Glycoprotein D
Heechung Kwon,Qing Bai,Hyunjung Baek,Kelly Felmet,Edward A. Burton,William F. Goins,Justus B. Cohen,Joseph C. Glorioso +7 more
TL;DR: The results demonstrate that the attachment function of gD is dispensable for entry provided that other means of attachment are available, such as gB and gC binding to cell surface glycosaminoglycans.
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Quantification of larval zebrafish motor function in multiwell plates using open-source MATLAB applications
TL;DR: This approach is widely applicable to the analysis of spontaneous or stimulus-evoked zebrafish larval neurobehavioral phenotypes resulting from a broad array of genetic and environmental manipulations, in a multiwell plate format suitable for high-throughput applications.
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Muscular Dystrophy—Reason for Optimism?
Edward A. Burton,Kay E. Davies +1 more
TL;DR: Characterization of the mechanisms underlying various types of muscular dystrophy has been an outstanding triumph of molecular biology, and increasing clarification of the aberrant cellular processes responsible for these conditions may ultimately permit the development of effective means for molecular intervention.
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