Edouard E. Galyov
University of Leicester
87 Papers
991 Citations
Edouard E. Galyov is an academic researcher from University of Leicester. The author has contributed to research in topics: Burkholderia pseudomallei & Biology. The author has an hindex of 40, co-authored 79 publications. Previous affiliations of Edouard E. Galyov include Umeå University & University of Bath.
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Papers
An Inv/Mxi-Spa-like type III protein secretion system in Burkholderia pseudomallei modulates intracellular behaviour of the pathogen.
Mark P. Stevens,Michael W. Wood,Lowrie A. Taylor,Paul Monaghan,Pippa Hawes,Philip W. Jones,Timothy S. Wallis,Edouard E. Galyov +7 more
TL;DR: Findings indicate that the Bsa type III secretion system plays an essential role in modulating the intracellular behaviour of B. pseudomallei.
322
A secreted effector protein of Salmonella dublin is translocated into eukaryotic cells and mediates inflammation and fluid secretion in infected ileal mucosa
Edouard E. Galyov,Michael W. Wood,Roland Rosqvist,Paul B. Mullan,Patricia R. Watson,Samantha Hedges,Tim S. Wallis +6 more
TL;DR: SopB, a novel secreted effector protein of Salmonella dublin is characterized, and data implying that SopB is translocated into eukaryotic cells via a sip‐dependent pathway to promote fluid secretion and inflammatory responses in the infected ileum are presented.
315
Complementary activities of SseJ and SifA regulate dynamics of the Salmonella typhimurium vacuolar membrane
Javier Ruiz-Albert,Xiu-Jun Yu,Carmen R. Beuzón,Abigail N. Blakey,Edouard E. Galyov,David W. Holden +5 more
TL;DR: Investigation of the role in S. typhimurium virulence of the putative SPI‐2 effector genes sifB, srfJ, sseJ and sseI suggests that the combined action of Sse j and SifA regulate dynamics of the SCV membrane in infected cells.
Molecular Insights into Burkholderia pseudomallei and Burkholderia mallei Pathogenesis
TL;DR: This review summarizes the current and rapidly expanding knowledge on the specific virulence factors employed by these pathogens and their roles in the pathogenesis of melioidosis and glanders.
244
Attenuated virulence and protective efficacy of a Burkholderia pseudomallei bsa type III secretion mutant in murine models of melioidosis.
Mark P. Stevens,Ashraful Haque,Timothy P. Atkins,James Hill,Michael W. Wood,Anna Easton,Michelle Nelson,Cindy Diana Underwood-Fowler,Richard W. Titball,Richard W. Titball,Gregory J. Bancroft,Edouard E. Galyov +11 more
TL;DR: B. pseudomallei bipD mutants, lacking a component of the translocation apparatus, were found to be significantly attenuated following intraperitoneal or intranasal challenge of BALB/c mice, indicating that bsa-encoded type III secreted proteins may act in concert to determine the outcome of B. pseudOMallei infection in mice.
204