Edmund B. Chen
Northwestern University
6 Papers
33 Citations
Edmund B. Chen is an academic researcher from Northwestern University. The author has contributed to research in topics: Neointimal hyperplasia & Restenosis. The author has an hindex of 3, co-authored 6 publications.
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Papers
The relationship of preoperative versus postoperative hyperglycemia on clinical outcomes after elective colorectal surgery.
TL;DR: Postoperative hyperglycemia was more significantly associated with adverse clinical outcomes after elective colorectal surgery than was preoperative hyper glycemia, suggesting that improved glycemic management preoperatively may help reduce hyperglycemic events after surgery.
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Microbiota control acute arterial inflammation and neointimal hyperplasia development after arterial injury
Kelly Wun,Betty Theriault,Joseph F. Pierre,Edmund B. Chen,Vanessa Leone,Katharine G. Harris,Liqun Xiong,Qun Jiang,Melanie Spedale,Owen M Eskandari,Eugene B. Chang,Karen J. Ho +11 more
TL;DR: GF mice have attenuated neointimal hyperplasia development compared to CONV-R mice, which is likely related to altered kinetics of wound healing and acute inflammation.
Current State of Knowledge on Implications of Gut Microbiome for Surgical Conditions.
TL;DR: A broad overview of the current state of knowledge and a review of the technology that helped in their formation of commensal gut microbiota is provided.
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Microbial Colonization of Germ-Free Mice Restores Neointimal Hyperplasia Development After Arterial Injury.
Edmund B. Chen,Katherine E. Shapiro,Kelly Wun,Thomas Kuntz,Betty Theriault,Michael J. Nooromid,Vanessa Leone,Katharine G. Harris,Qun Jiang,Melanie Spedale,Liqun Xiong,Jack A. Gilbert,Eugene B. Chang,Karen J. Ho +13 more
TL;DR: Germ‐free mice have significantly attenuated neointimal hyperplasia development compared with conventionally raised mice, and the arterial remodeling response is restored by fecal transplantation.
Microbiota composition modulates inflammation and neointimal hyperplasia after arterial angioplasty.
Cori A. Cason,Thomas Kuntz,Edmund B. Chen,Kelly Wun,Michael J. Nooromid,Liqun Xiong,Neil Gottel,Katharine G. Harris,Timothy Morton,Michael J. Avram,Eugene B. Chang,Jack A. Gilbert,Karen J. Ho +12 more
TL;DR: A novel mechanism for how microbiome manipulations affect arterial remodeling and the inflammatory response after arterial injury is described and could uncover novel therapeutic targets for the prevention and treatment of restenosis.
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