E. V. Berezhnaya
Southern Federal University
25 Papers
89 Citations
E. V. Berezhnaya is an academic researcher from Southern Federal University. The author has contributed to research in topics: Neuron & Sensory neuron. The author has an hindex of 7, co-authored 21 publications. Previous affiliations of E. V. Berezhnaya include New York University.
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Papers
Involvement of nitric oxide in photodynamic injury of neurons and glial cells.
TL;DR: Application of various inhibitors of NO synthase showed that the anti-necrotic effect of NO could be related, at least in glial cells, to its production by neuronal rather than inducible isoform of this enzyme.
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Photo-Induced Oxidative Stress Impairs Mitochondrial Metabolism in Neurons and Astrocytes
TL;DR: Investigation of the cellular mechanism of photodynamic action of radachlorin on neurons and astrocytes in primary rat cell culture found that it leads to activation of PARP and decrease in NADH that leads to mitochondrial dysfunction.
Involvement of MAPK, Akt/GSK-3β and AMPK/mTOR signaling pathways in protection of remote glial cells from axotomy-induced necrosis and apoptosis in the isolated crayfish stretch receptor
E. V. Berezhnaya,M.Y. Bibov,M. A. Komandirov,M. A. Neginskaya,M. V. Rudkovskii,Anatoly B. Uzdensky +5 more
TL;DR: The use of the crayfish stretch receptor as a model object for the study of the role of various signaling proteins in axotomy‐induced death of remote glial cells suggests the involvement of these proteins in protective, antiapoptotic and antinecrotic processes in the remote satellite glia surrounding the axotomized mechanoreceptor neuron.
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Са2+- and NF-κB-dependent generation of NO in the photosensitized neurons and satellite glial cells.
TL;DR: It is shown that Ca2+ and NF-κB regulate NO generation in the photosensitized neurons and glia, suggesting the involvement of bothCa2+-dependent neuronal NO synthase and Ca2-independent inducibleNO synthase, which is regulated by NF-kkB, in NO production in the crayfish neurons andglia.
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Photodynamic effect of Radachlorin on nerve and glial cells
TL;DR: Radachlorin rapidly accumulates in the nervous tissue, mainly in glial cells, and demonstrates very high photodynamic efficacy that characterize it as a promising photosensitizer.
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