Dung T. Do
Indiana University
6 Papers
12 Citations
Dung T. Do is an academic researcher from Indiana University. The author has contributed to research in topics: Enantioselective synthesis & Catalysis. The author has an hindex of 4, co-authored 6 publications.
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Papers
Uniting C1-Ammonium Enolates and Transition Metal Electrophiles via Cooperative Catalysis: The Direct Asymmetric α-Allylation of Aryl Acetic Acid Esters
TL;DR: This conceptual approach to cooperative catalysis constitutes a potentially general solution to the direct catalytic asymmetric α-functionalization of acyclic esters.
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ThX – a next-generation probe for the early detection of amyloid aggregates
Lisa-Maria Needham,Judith Weber,Juan A. Varela,James W. B. Fyfe,Dung T. Do,Catherine K. Xu,Luke Tutton,Rachel Cliffe,Benjamin Keenlyside,David Klenerman,Christopher M. Dobson,Christopher A. Hunter,Karin H. Müller,Kevin O'Holleran,Sarah E. Bohndiek,Thomas N. Snaddon,Steven F. Lee +16 more
TL;DR: Thioflavin X, (ThX), a next-generation fluorescent probe which displays superior properties; including a 5-fold increase in brightness and 7-fold increased in binding affinity to amyloidogenic proteins, is designed.
Bifunctional fluorescent probes for detection of amyloid aggregates and reactive oxygen species.
Lisa-Maria Needham,Judith Weber,James W. B. Fyfe,Omaru M. Kabia,Dung T. Do,Ewa Klimont,Yu Zhang,Margarida Rodrigues,Christopher M. Dobson,Sonia Ghandi,Sarah E. Bohndiek,Thomas N. Snaddon,Steven F. Lee +12 more
TL;DR: Four highly sensitive bifunctional fluorescent probes, capable of H2O2 and/or amyloid aggregate detection, are created and results indicate these new probes will be useful to detect and monitor neurodegenerative disease.
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ThX - A next-generation probe for the early detection of amyloid aggregates
Lisa-Maria Needham,Judith Weber,Juan A. Varela,James W. B. Fyfe,Dung T. Do,Catherine K. Xu,Benjamin Keenlyside,Rachel Cliffe,David Klenerman,Christopher M. Dobson,Christopher A. Hunter,Sarah E. Bohndiek,Thomas N. Snaddon,Steven F. Lee +13 more
TL;DR: Thioflavin X, (ThX), a next-generation fluorescent probe which displays superior properties and can be used to study unique structural amyloid features both in bulk and on a single-aggregate level, is designed and used as a super-resolution imaging probe in single-molecule localisation microscopy.
Uniting C1‐Ammonium Enolates and Transition Metal Electrophiles via Cooperative Catalysis: The Direct Asymmetric α‐Allylation of Aryl Acetic Acid Esters.
TL;DR: In this article, the authors proposed a conceptual approach to cooperative α-allylation of aryl acetic acid esters, where enantioselection is determined by the nucleophile, which constitutes a potentially general solution to direct catalytic asymmetric α-functionalization of acyclic esters.
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