Dorothée Gößl
Ludwig Maximilian University of Munich
6 Papers
Dorothée Gößl is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: Mesoporous silica & Drug delivery. The author has an hindex of 6, co-authored 6 publications. Previous affiliations of Dorothée Gößl include Nanosystems Initiative Munich.
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Papers
Mesoporous Silica Nanoparticles as pH-Responsive Carrier for the Immune-Activating Drug Resiquimod Enhance the Local Immune Response in Mice.
Julia Wagner,Dorothée Gößl,Natasha Ustyanovska,Mengyao Xiong,Daniel Hauser,Olga Zhuzhgova,Sandra Hočevar,Betül Taskoparan,Laura M. Poller,Stefan Datz,Hanna Engelke,Youssef Daali,Thomas Bein,Carole Bourquin +13 more
TL;DR: In this article, the potential of mesoporous silica nanoparticles as a pH-responsive drug carrier system for the anticancer immune-stimulant R848 (resiquimod) was demonstrated.
Immune response to functionalized mesoporous silica nanoparticles for targeted drug delivery
Simon Heidegger,Simon Heidegger,Dorothée Gößl,Alexandra Schmidt,Stefan Niedermayer,Christian Argyo,Stefan Endres,Thomas Bein,Carole Bourquin,Carole Bourquin +9 more
TL;DR: In this article, the authors assess the biocompatibility and functionality of multifunctional mesoporous silica nanoparticles (MSN) in freshly isolated, primary murine immune cells and demonstrate that MSN represent an efficient drug delivery vehicle to primary immune cells that is both non-toxic and non-inflammagenic.
Immune response to functionalized mesoporous silica nanoparticles for targeted drug delivery
Simon Heidegger,Simon Heidegger,Stefan Niedermayer,Alexandra Schmidt,Dorothée Gößl,Christian Argyo,Stefan Endres,Thomas Bein,Carole Bourquin,Carole Bourquin +9 more
TL;DR: It is demonstrated that MSN represent an efficient drug delivery vehicle to primary immune cells that is both non-toxic and non-inflammagenic, which is a prerequisite for the use of these particles in biomedical applications.
Highly active enzymes immobilized in large pore colloidal mesoporous silica nanoparticles
Dorothée Gößl,Helena Singer,Hsin-Yi Chiu,Alexandra Schmidt,Martina Lichtnecker,Hanna Engelke,Thomas Bein +6 more
TL;DR: Carbonic anhydrase and horseradish peroxidase are immobilized inside the ordered material by click reactions and colorimetric assays prove their catalytic activity.
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Clickable Multifunctional Large-Pore Mesoporous Silica Nanoparticles as Nanocarriers
TL;DR: In this paper, a delayed co-condensation strategy was applied to create spatially segregated core-shell bifunctional large-pore mesoporous silica nanoparticles.