Doo Yang
University of Ottawa
7 Papers
Doo Yang is an academic researcher from University of Ottawa. The author has contributed to research in topics: Chromatin remodeling & Histone. The author has an hindex of 5, co-authored 7 publications.
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Papers
Snf2h-mediated chromatin organization and histone H1 dynamics govern cerebellar morphogenesis and neural maturation
Matías Alvarez-Saavedra,Matías Alvarez-Saavedra,Yves De Repentigny,Pamela S. Lagali,Edupuganti V.S. Raghu Ram,Keqin Yan,Emile Hashem,Emile Hashem,Danton Ivanochko,Danton Ivanochko,Michael S. Huh,Doo Yang,Alan J. Mears,Matthew A. M. Todd,Matthew A. M. Todd,Chelsea P. Corcoran,Erin A. Bassett,Nicholas Tokarew,Juraj Kokavec,Romit Majumder,Ilya Ioshikhes,Valerie A. Wallace,Valerie A. Wallace,Rashmi Kothary,Rashmi Kothary,Eran Meshorer,Tomas Stopka,Arthur I. Skoultchi,David J. Picketts,David J. Picketts +29 more
TL;DR: It is shown that mice conditionally inactivated for Snf2h in neural progenitors have reduced levels of histone H1 and H2A variants that compromise chromatin fluidity and transcriptional programs within the developing cerebellum.
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Voluntary Running Triggers VGF-Mediated Oligodendrogenesis to Prolong the Lifespan of Snf2h-Null Ataxic Mice
Matías Alvarez-Saavedra,Matías Alvarez-Saavedra,Matías Alvarez-Saavedra,Yves De Repentigny,Doo Yang,Ryan W. O'Meara,Ryan W. O'Meara,Keqin Yan,Lukas E. Hashem,Lukas E. Hashem,Lemuel Racacho,Lemuel Racacho,Ilya Ioshikhes,Dennis E. Bulman,Dennis E. Bulman,Robin J. Parks,Robin J. Parks,Rashmi Kothary,Rashmi Kothary,David J. Picketts,David J. Picketts +20 more
TL;DR: It is shown that voluntary running induced an endogenous brain repair mechanism that resulted in a striking increase in hindbrain myelination and the long-term survival of Snf2h cKO mice, and the VGF growth factor was identified as a major driver underlying this effect.
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Effects of Chronic Low-Dose Internal Radiation on Immune-Stimulatory Responses in Mice.
Abrar Ul Haq Khan,Melinda Blimkie,Doo Yang,Mandy L Serran,Tyler Pack,Jin Wu,Ji-Young Kang,Holly Laakso,Seung-Hwan Lee,Yevgeniya Le,Yevgeniya Le +10 more
TL;DR: In this article, the effects of LDR on the development and progression of mammary cancer in FVB/N-Tg(MMTVneu)202Mul/J mice were investigated.
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Nucleosome Presence at AML-1 Binding Sites Inversely Correlates with Ly49 Expression: Revelations from an Informatics Analysis of Nucleosomes and Immune Cell Transcription Factors.
TL;DR: The data suggest that nucleosomal-based regulation contributes to the expression of Ly49 genes, and it is proposed that this method of predicting nucleosome sensitivity could aid in dissecting the regulatory role of nucleosomes in general.
Snf2h Drives Chromatin Remodeling to Prime Upper Layer Cortical Neuron Development.
Matías Alvarez-Saavedra,Matías Alvarez-Saavedra,Matías Alvarez-Saavedra,Keqin Yan,Yves De Repentigny,Lukas E. Hashem,Nidhi Chaudary,Shihab Sarwar,Doo Yang,Ilya Ioshikhes,Rashmi Kothary,Rashmi Kothary,Teruyoshi Hirayama,Teruyoshi Hirayama,Takeshi Yagi,David J. Picketts,David J. Picketts +16 more
TL;DR: It is shown that inactivation of the closely related Smarca5 gene encoding the Snf2h chromatin remodeler is necessary for embryonic IPC expansion and subsequent specification of callosal projection neurons.