Donna Wilton
Imperial College London
5 Papers
2 Citations
Donna Wilton is an academic researcher from Imperial College London. The author has contributed to research in topics: Aryne & Ring-closing metathesis. The author has an hindex of 2, co-authored 5 publications. Previous affiliations of Donna Wilton include University of Cambridge.
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Papers
Alkynes to (E)-enolates using tandem catalysis: stereoselective anti-aldol and syn-[3,3]-rearrangement reactions
Neil P. Grimster,Donna Wilton,Louis K. M. Chan,Christopher Richard Ayles Godfrey,Clive Green,Dafydd R. Owen,Matthew J. Gaunt +6 more
TL;DR: A new tandem catalysis strategy that transforms alkyne derivatives to (E)-enol-equivalents followed by stereoselective anti-selective aldol coupling or syn- selective [3,3]-rearrangement transformations is reported.
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Highly Convergent Three-Component Benzyne Coupling: The Total Synthesis of ent-Clavilactone B.
Igor Larrosa,Marianne I. Da Silva,Patricio M. Gomez,Peter Hannen,Eunjung Ko,Steven R. Lenger,Simon R. Linke,Andrew J. P. White,Donna Wilton,Anthony G. M. Barrett +9 more
TL;DR: The first total synthesis of (+)-clavilactone B, a potent antifungal agent and novel tyrosine kinase inhibitor, is described in this paper, which highlights the use of a powerful and convergent three-component benzyne coupling with a methylallyl Grignard and a chiral epoxy-aldehyde.
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Alkynes to (E)‐Enolates Using Tandem Catalysis: Stereoselective anti‐Aldol and syn‐[3,3]‐Rearrangement Reactions.
Neil P. Grimster,Donna Wilton,Louis K. M. Chan,Christopher Richard Ayles Godfrey,Clive Green,Dafydd R. Owen,Matthew J. Gaunt +6 more
TL;DR: In this paper, a new tandem catalysis strategy was developed, which transforms alkyne derivatives into (E)-enol equivalents, and a new method was proposed to solve the problem.
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[2,6‐Bis(1‐methylethyl)benzenaminato‐(2) [bis(1,1,1,3,3,3‐hexafluoro‐2‐methyl‐2‐ propanolato)(2‐methyl‐2‐phenylpropylidene) molybdenum (Schrock's Catalyst)
Daniel P. Christen,Anthony G. M. Barrett,Donna Wilton +2 more
- 15 Sep 2006
TL;DR: InChI as mentioned in this paper is a reagent used for a wide range of catalyzed ring-closing and ring-opening metathesis reactions, such as ring closing and ring opening.
Highly Convergent Three Component Benzyne Coupling: The Total Synthesis of ent-Clavilactone B
Igor Larrosa,Marianne I. Da Silva,Patricio M. Gomez,Peter Hannen,Eunjung Ko,Steven R. Lenger,Simon R. Linke,Andrew J. P. White,Donna Wilton,Anthony G. M. Barrett +9 more
TL;DR: The first total synthesis of (+)-clavilactone B, a potent antifungal agent and novel tyrosine kinase inhibitor, is described, using Sharpless asymmetric epoxidation to generate the enantiomerically pure substrate.