Dong M. Shin
Emory University
399 Papers
3.1K Citations
Dong M. Shin is an academic researcher from Emory University. The author has contributed to research in topics: Cancer & Medicine. The author has an hindex of 79, co-authored 368 publications. Previous affiliations of Dong M. Shin include Georgia Institute of Technology & Radiation Therapy Oncology Group.
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Papers
Predictive value of gene expression signatures in premalignant lesions of the head and neck for response to chemoprevention with EGFR and COX-2 inhibitors.
Nabil F. Saba,Michael R. Rossi,Bhakti Dwivedi,Jeffrey M. Switchenko,Kelly R. Magliocca,Suresh S. Ramalingam,Taofeek K. Owonikoko,Fadlo R. Khuri,Zhuo Georgia Chen,Jeanne Kowalski,Dong M. Shin +10 more
TL;DR: The presence of a genomic signature that can predict outcome in patients with pre-malignant lesions using expression data by the nCOunter nanoString platform is explored.
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Association of epigenetic age acceleration with risk factors, survival, and quality of life in patients with head and neck cancer
Canhua Xiao,Andrew H. Miller,Gang Peng,Morgan E. Levine,Karen N. Conneely,Hongyu Zhao,Ronald C. Eldridge,Evanthia C. Wommack,Sangchoon Jeon,Kristin Higgins,Dong M. Shin,Nabil F. Saba,Alicia K. Smith,Barbara Burtness,Henry S. Park,Melinda L. Irwin,Leah M. Ferrucci,Bryan C. Ulrich,David C. Qian,Jonathan J. Beitler,Deborah Watkins Bruner +20 more
TL;DR: In this article, the authors examined risk factors of EAA and its association with overall survival (OS), progression-free survival (PFS), and quality of life (QOL) in patients with head and neck cancer (HNC) receiving radiation therapy.
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Abstract 3154: RSK2-mediated phosphorylation of stathmin promotes microtubule polymerization, providing a pro-invasive advantage to metastatic cancer cells
TL;DR: This finding demonstrates that RSK2 signals through STMN to regulate microtubule polymerization and cancer cell invasion via direct phosphorylation of STMN at Serine 16, providing a pro-invasive and metastatic advantage to cancer cells.
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Dual targeting of EGFR and HER3 with cetuximab and MM-121/SAR256212 in HNSCC patient derived xenograft (PDX) models.
Nabil F. Saba,Dongsheng Wang,Guoquing Qian,Hongzheng Zhang,Mihir R. Patel,Mark W. El-Deiry,J. Trad Wadsworth,Kelly R. Magliocca,Sreevinas Nannapaneni,Dong M. Shin,Fadlo R. Khuri,Zhuo Georgia Chen +11 more
TL;DR: Cetuximab induced HER3 activation in cell lines; the combined treatment blocked EGFR and HER3 and inhibited PI3K/AKT and ERK as well as preventing EGFR-targeted therapy in head and neck squamous cell carcinoma.
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Abstract 3903: Optimizing the antitumor efficacy of AuNR-assisted plasmonic photothermal therapy and its molecular impact
Mohammad Aminur Rahman,Moustafa R. K. Ali,Zhixiang Zhao,Georgia Z. Chen,Mostafa A. El-Sayed,Dong M. Shin +5 more
TL;DR: This study conducted an in vivo antitumor efficacy study in nude mice bearing human HNSCC Tu686 xenograft tumors with three formulations of AuNRs (72×19 nm and 26×6 nm with or without rifampicin (Rf) conjugation), and found small AuNR-conjugated Rf (AuNR-Rf), had very significant antitumors efficacy at high laser power.
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