13 Papers
8 Citations
Dong Li is an academic researcher from Shanghai Jiao Tong University. The author has contributed to research in topics: Innate immune system & Cancer. The author has an hindex of 7, co-authored 11 publications. Previous affiliations of Dong Li include Zhejiang University.
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Papers
Inducible microRNA-155 Feedback Promotes Type I IFN Signaling in Antiviral Innate Immunity by Targeting Suppressor of Cytokine Signaling 1
Pin Wang,Jin Hou,Li Lin,Chunmei Wang,Xingguang Liu,Dong Li,Feng Ma,Zhugang Wang,Xuetao Cao,Xuetao Cao +9 more
TL;DR: It is demonstrated that inducible miR-155 feedback positively regulates host antiviral innate immune response by promoting type I IFN signaling via targeting SOCS1.
MicroRNA-148/152 Impair Innate Response and Antigen Presentation of TLR-Triggered Dendritic Cells by Targeting CaMKIIα
TL;DR: It is shown that miR-148/152 can act as fine-tuner in regulating the innate response and Ag-presenting capacity of DCs, which may contribute to the immune homeostasis and immune regulation.
284
Intracellular MHC class II molecules promote TLR-triggered innate immune responses by maintaining activation of the kinase Btk
Xingguang Liu,Zhenzhen Zhan,Dong Li,Li Xu,Feng Ma,Peng Zhang,Hangping Yao,Xuetao Cao,Xuetao Cao +8 more
TL;DR: It is reported that deficiency in MHC class II attenuated the TLR-triggered production of proinflammatory cytokines and type I interferon in macrophages and dendritic cells, which protected mice from endotoxin shock.
269
MicroRNA-99a Inhibits Hepatocellular Carcinoma Growth and Correlates with Prognosis of Patients with Hepatocellular Carcinoma
Dong Li,Xingguang Liu,Li Lin,Jin Hou,Nan Li,Chunmei Wang,Pin Wang,Qian Zhang,Peng Zhang,Weiping Zhou,Zhengxin Wang,Guoshan Ding,Shi-Mei Zhuang,Limin Zheng,Wenzhao Tao,Xuetao Cao,Xuetao Cao +16 more
TL;DR: Conclusively, miR-99a expression was frequently down-regulated in HCC tissues and correlates with the prognosis of HCC patients, thus proposing miR -99a as a prospective prognosis predictor and therapeutic approach for HCC.
254
Late Endosome/Lysosome-Localized Rab7b Suppresses TLR9-Initiated Proinflammatory Cytokine and Type I IFN Production in Macrophages
TL;DR: The results suggest that the late endosome/lysosome-localized Rab7b can down-regulate TLR9-triggered proinflammatory cytokine and type I IFN production by impairingTLR9 signaling via promotion of TLR 9 degradation.