Dong Chen
Chinese Academy of Sciences
10 Papers
19 Citations
Dong Chen is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Total synthesis & Semipinacol rearrangement. The author has an hindex of 6, co-authored 10 publications.
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Papers
Concise synthesis of (±)-Lingzhiol via epoxy-arene cyclization
Dong Chen,Hao-Miao Liu,Ming-Ming Li,Yong-Min Yan,Wen-Dan Xu,Xiao-Nian Li,Yong-Xian Cheng,Hong-Bo Qin +7 more
TL;DR: Concise synthesis of (±)-Lingzhiol has been achieved through one-step construction of a 5/5/6/6 tetra-ring backbone of Lingzhiol via epoxy-arene cyclization.
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Enantioselective total synthesis of (+)-Lingzhiol via tandem semipinacol rearrangement/Friedel-Crafts type cyclization
Dong Chen,Wen-Dan Xu,Hao-Miao Liu,Ming-Ming Li,Yong-Min Yan,Xiao-Nian Li,Yan Li,Yong-Xian Cheng,Hong-Bo Qin +8 more
TL;DR: The (+)-Lingzhiol synthesis is the first example of in tandem semipinacol rearrangement reactions, the migrated aryl group further reacting with the carbonyl oxonium electrophile to furnish a polycyclic skeleton.
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Total Synthesis of (±)-Cochlearol A
TL;DR: Total synthesis of (±)-cochlearol A was accomplished, which features a cis 6/6 B/D ring synthesis, which involves a TMSOTf-promoted lactonization of tert-butoxy ketoester and a cis configuration of the B/E ring.
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Synthesis of trisaccharide repeating unit of fucosylated chondroitin sulfate
TL;DR: The chemical synthesis of a sulfated trisaccharide repeating unit of fucosylated chondroitin sulfate (FCS) has significant anticoagulant activity and could be used to extend oligosaccharides sequences.
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Catalytic asymmetric formal total synthesis of (+)-dichroanone and (+)-taiwaniaquinone H
Liang-Qun Li,Liang-Qun Li,Ming-Ming Li,Dong Chen,Hao-Miao Liu,Hui-Chun Geng,Jun Lin,Hong-Bo Qin +7 more
TL;DR: In this article, a formal total synthesis of (+)-dichroanone and (+)-taiwaniaquinone H has been achieved, and the main step involved construction of all-carbon quaternary carbon by palladium-catalyzed conjugate addition of arylboronic acid to 3-methyl cyclohexenone.
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