Donatella Gniuli
Catholic University of the Sacred Heart
25 Papers
329 Citations
Donatella Gniuli is an academic researcher from Catholic University of the Sacred Heart. The author has contributed to research in topics: Insulin & Insulin resistance. The author has an hindex of 16, co-authored 25 publications. Previous affiliations of Donatella Gniuli include The Catholic University of America.
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Papers
Mechanisms of Recovery From Type 2 Diabetes After Malabsorptive Bariatric Surgery
Caterina Guidone,Melania Manco,Elena Valera-Mora,Amerigo Iaconelli,Donatella Gniuli,Andrea Mari,Giuseppe Nanni,Marco Castagneto,Menotti Calvani,Geltrude Mingrone +9 more
TL;DR: BPD determines a prompt reversibility of type 2 diabetes by normalizing peripheral insulin sensitivity and enhancing β-cell sensitivity to glucose, these changes occurring very early after the operation.
375
Insulin resistance directly correlates with increased saturated fatty acids in skeletal muscle triglycerides
Melania Manco,AV Greco,Esmeralda Capristo,Donatella Gniuli,A. De Gaetano,Giovanni Gasbarrini +5 more
TL;DR: Not only the MTG concentration but also the FFA pattern seems to affect insulin-mediated glucose uptake, and a pivotal role might be played by a high saturated fatty acid content in the TGs.
196
Effects of Bilio-Pancreatic Diversion on Diabetic Complications: A 10-year follow-up
Amerigo Iaconelli,Simona Panunzi,Andrea De Gaetano,Melania Manco,Caterina Guidone,Laura Leccesi,Donatella Gniuli,Giuseppe Nanni,Marco Castagneto,Giovanni Ghirlanda,Geltrude Mingrone +10 more
TL;DR: Renal and cardiovascular complications were dramatically reduced in the surgical arm, indicating long-term benefits of BPD on diabetic complications, at least in the case of morbid obesity with decompensated type 2 diabetes.
145
Effects of high-fat diet exposure during fetal life on type 2 diabetes development in the progeny
Donatella Gniuli,Alessandra Calcagno,Maria Emiliana Caristo,Alessandra Mancuso,Veronica Macchi,Geltrude Mingrone,Roberto Vettor +6 more
TL;DR: In this paper, the effects of high-fat diets on the development of Type 2 diabetes in young adult mice were investigated, and the authors concluded that a high fat diet during fetal life can induce the type 2 diabetes phenotype, which can be directly transmitted to the progeny even in the absence of additional dietary insults.
90
High-fat feeding stimulates endocrine, glucose-dependent insulinotropic polypeptide (GIP)-expressing cell hyperplasia in the duodenum of Wistar rats.
Donatella Gniuli,Alessandra Calcagno,L. Dalla Libera,Riccardo Calvani,Laura Leccesi,Me Caristo,Roberto Vettor,Marco Castagneto,Giovanni Ghirlanda,G. Mingrone +9 more
TL;DR: This study shows that HFD stimulates duodenal proliferation of endocrine cells differentiating towards K cells and oversecreting GIP, which might represent the stimulus for insulin hypersecretion and insulin resistance.