Donald Jones
2 Papers
Donald Jones is an academic researcher. The author has contributed to research in topics: Antibody & Epitope. The author has co-authored 2 publications.
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Papers
Epitope Mapping by Molecular Imprinting of Adeno-Associated Virus Serotype 8(AAV8)-Antibody Complexes and Use of Fab Peptides as a Novel Strategy of Evadingneutralisation to Improve the Efficiency of AAV8-Mediated Gene Therapy
Elena V. Piletska,Philippe Veron,Bérangère Bertin,Federico Mingozzi,Donald Jones,Joseph Earley,Kal Karim,Alvaro Garcia Cruz,Sergey A. Piletsky +8 more
Analysis of Adeno-Associated Virus Serotype 8 (AAV8)-antibody complexes using epitope mapping by molecular imprinting leads to the identification of Fab peptides that potentially evade AAV8 neutralisation.
Elena V. Piletska,Philippe Veron,Bérangère Bertin,Federico Mingozzi,Donald Jones,Rachel L. Norman,Joseph Earley,Kal Karim,Alvaro Garcia-Cruz,Sergey A. Piletsky +9 more
TL;DR: In this paper , a molecular imprinting technique combined with mass-spectrometry and bioinformatics was used to identify four antigen-binding fragments (Fab) sequences of Adeno-Associated Virus (AAV) -neutralising antibodies capable of binding to AAV.