Domenico Ribatti
University of Bari
965 Papers
6.1K Citations
Domenico Ribatti is an academic researcher from University of Bari. The author has contributed to research in topics: Angiogenesis & Biology. The author has an hindex of 96, co-authored 913 publications. Previous affiliations of Domenico Ribatti include University of Genoa & National Institutes of Health.
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Papers
Effects of exogenous heparin on the vasculogenesis of the chorioallantoic membrane.
TL;DR: The results, confirming that heparin is involved in angiogenesis, indicate the suitability of the technique and suggest that the effects of this substance could be enhanced by growth factors released by CAM tissues rapidly growing up from the 5th to the 7th incubation day.
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In vivo angiogenic activity of urokinase: role of endogenous fibroblast growth factor-2.
Domenico Ribatti,Daria Leali,Angelo Vacca,Roberta Giuliani,Anna Gualandris,Luisa Roncali,Maria Luisa Nolli,Marco Presta +7 more
TL;DR: The data indicate that uPA is able to induce angiogenesis in vivo via a plasmin-dependent degradation of ECM that causes the mobilization of stored endogenous FGF2.
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Chorioallantoic membrane for in vivo investigation of tissue-engineered construct biocompatibility.
TL;DR: The results till now obtained suggest that CAM assay can be used as a pre-screening assay, before in vivo animal studies, to determine whether the scaffold is liable to cause an adverse reaction and to evaluate its future enhancement of existing materials for tissue engineering.
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In vitro and in vivo evaluation of acellular diaphragmatic matrices seeded with muscle precursors cells and coated with VEGF silica gels to repair muscle defect of the diaphragm.
Maria Teresa Conconi,Silvia Bellini,Debora Teoli,Paolo De Coppi,Domenico Ribatti,Beatrice Nico,Enea Simonato,Pier G. Gamba,Gastone G. Nussdorfer,Margherita Morpurgo,P.P. Parnigotto +10 more
TL;DR: Results confirmed that the matrices contained biologically active angiogenic factors which were per se sufficient to induce neo-vessels formation, thus allowing the survival of implanted myoblasts, as well as demonstrating that the silica support was nontoxic and the VEGF bioactivity was maintained after matrix entrapment.
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Selective therapeutic targeting of the anaplastic lymphoma kinase with liposomal siRNA induces apoptosis and inhibits angiogenesis in neuroblastoma.
Daniela Di Paolo,Chiara Ambrogio,Fabio Pastorino,Chiara Brignole,Cinzia Martinengo,R. Carosio,Monica Loi,Gabriella Pagnan,Laura Emionite,Michele Cilli,Domenico Ribatti,Theresa M. Allen,Roberto Chiarle,Mirco Ponzoni,Patrizia Perri +14 more
TL;DR: In mice, a nanodelivery system for ALK-specific small interfering RNA (siRNA), based on the conjugation of antibodies directed against the NB-selective marker GD(2) to liposomes, showed strong ALK knockdown in vivo in NB cells, which resulted in cell growth arrest, apoptosis, and prolonged survival.
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