Domenico Ribatti
University of Bari
965 Papers
6.1K Citations
Domenico Ribatti is an academic researcher from University of Bari. The author has contributed to research in topics: Angiogenesis & Biology. The author has an hindex of 96, co-authored 913 publications. Previous affiliations of Domenico Ribatti include University of Genoa & National Institutes of Health.
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Papers
“Sprouting angiogenesis”, a reappraisal
TL;DR: This review article will provide a brief overview of some relevant topics defining sprouting angiogenesis, including functional specialization of endothelial cells during different phases of this process, and some fundamental and consecutive morphological processes, leading to the final vessel maturation and stabilization.
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•Journal Article
Vascular Damage and Anti-angiogenic Effects of Tumor Vessel-Targeted Liposomal Chemotherapy
Fabio Pastorino,Chiara Brignole,Danilo Marimpietri,Michele Cilli,Claudio Gambini,Domenico Ribatti,Renato Longhi,Theresa M. Allen,Angelo Corti,Mirco Ponzoni +9 more
TL;DR: A dual mechanism of action is proposed: indirect tumor cell kill via the destruction of tumor endothelium by NGR-targeted liposomes and direct tumorcell kill via localization of liposomal DXR to the tumor interstitial space and has the potential to overcome some major limitations of conventional chemotherapy.
316
Chorioallantoic membrane capillary bed: a useful target for studying angiogenesis and anti-angiogenesis in vivo.
TL;DR: A new model of the CAM vascular growth, namely the intussusceptive mode, is described, which reports findings regarding the role played by endogenous fibroblast growth factor‐2 in CAM vascularization.
312
Mammalian Tumor Xenografts Induce Neovascularization in Zebrafish Embryos
TL;DR: The zebrafish/tumor xenograft model represents a novel tool for investigating the neovascularization process exploitable for drug discovery and gene targeting in tumor angiogenesis and VE-cadherin gene inactivation by antisense morpholino oligonucleotide injection inhibits tumor neov vessel development.
296
The chick embryo chorioallantoic membrane (CAM). A multifaceted experimental model.
TL;DR: The chorioallantoic membrane is a relatively simple, quick, and low-cost model that allows screening of a large number of pharmacological samples in a short time; does not require administrative procedures for obtaining ethics committee approval for animal experimentation.
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