Domenico Ribatti
University of Bari
965 Papers
6.1K Citations
Domenico Ribatti is an academic researcher from University of Bari. The author has contributed to research in topics: Angiogenesis & Biology. The author has an hindex of 96, co-authored 913 publications. Previous affiliations of Domenico Ribatti include University of Genoa & National Institutes of Health.
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Papers
Antiangiogenic Activity of Semisynthetic Biotechnological Heparins Low-Molecular-Weight-Sulfated Escherichia coli K5 Polysaccharide Derivatives as Fibroblast Growth Factor Antagonists
Marco Presta,Pasqua Oreste,Giorgio Zoppetti,Mirella Belleri,Elena Tanghetti,Daria Leali,Chiara Urbinati,Antonella Bugatti,Roberto Ronca,Stefania Nicoli,Emanuela Moroni,Helena Stabile,Maura Camozzi,German Andrés Hernandez,Stefania Mitola,Patrizia Dell'Era,Marco Rusnati,Domenico Ribatti +17 more
TL;DR: The fibroblast growth factor-2 (FGF2) antagonist and antiangiogenic activity of a series of LMW N,O-sulfated K5 derivatives are investigated and these compounds may provide the basis for the design of novel LMW heparin-like angiostatic compounds.
In vitro and in vivo angiogenic activity of osteoarthritic and osteoporotic osteoblasts is modulated by VEGF and vitamin D3 treatment.
Anna Neve,Francesco Paolo Cantatore,Addolorata Corrado,Annamaria Gaudio,Simona Ruggieri,Domenico Ribatti +5 more
TL;DR: Evaluated in vitro differences in VEGF production and expression of cultured human osteoblastic cells derived from healthy donors and from subjects affected by osteoarthritis and osteoporosis showed that normal and pathological osteoblasts produce and express V EGF and 1,25 dihydroxy-vitamin D3 treatment increases protein and m-RNA VEGf levels.
Endothelialization approaches for viable engineered tissues
Silvia Baiguera,Domenico Ribatti +1 more
TL;DR: This review provides an overview of the different techniques developed so far for the vascularization of tissue-engineered constructs (with their advantages and pitfalls), focusing the attention on the recent development in the cell-based vascularization strategy and the in vivo applications.
Serum tryptase, mast cells positive to tryptase and microvascular density evaluation in early breast cancer patients: possible translational significance
Ilaria Marech,Michele Ammendola,Rosario Sacco,Gennaro Stefano Capriuolo,Rosa Patruno,Rosangela Rubini,Maria Luposella,Valeria Zuccalà,Eufemia Savino,Cosmo Damiano Gadaleta,Domenico Ribatti,Girolamo Ranieri +11 more
TL;DR: Serum tryptase levels may play a role as a novel surrogate angiogenic marker predictive of response to radical surgery in breast cancer patients, indicating an involvement of MCtryptase in Breast cancer angiogenesis.
Activation of endothelial cell mitogen activated protein kinase ERK(1/2) by extracellular HIV-1 Tat protein.
Marco Rusnati,Chiara Urbinati,B. Musulin,Domenico Ribatti,Adriana Albini,Douglas M. Noonan,C. Marchisone,Johannes Waltenberger,Marco Presta +8 more
TL;DR: Recombinant Tat protein, produced as glutathione-S-transferase chimera (GST-Tat), activates mitogen-activated protein kinase (MAPK) ERK(1/2) in human, murine, and bovine endothelial cells whereas GST is ineffective and blocking of MAPK kinase activity impairs instead the angiogenic response to VEGF165 and to fibroblast growth factor-2 (FGF-2).